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Background: The CpG island methylator phenotype (CIMP), characterised by widespread promoter methylation, is associated with… Expand Background The CpG island methylator phenotype (CIMP) is a distinct phenotype associated with microsatellite instability (MSI… Expand The CpG island methylator phenotype (CIMP) with widespread promoter CpG island methylation is a phenotype in colorectal cancer… Expand The CpG island methylator phenotype (CIMP or CIMP-high) with extensive promoter methylation is a distinct phenotype in colorectal… Expand BackgroundThe epigenetics of ovarian carcinogenesis remains poorly described. We have in the present study investigated the… Expand PURPOSE
An estimated 4% to 7% of the population will develop a clinically significant thyroid nodule during their lifetime. In… Expand Apart from the retinoic acid nuclear receptor family, there are two low molecular weight (15 kD) cellular retinoic acid binding… Expand The cellular retinoic acid binding proteins I and II (CRABPI and CRABPII) bind retinoic acid with high affinity, exhibit distinct… Expand The CRABP-I and CRABP-II proteins are high affinity cytoplasmic retinoic acid-binding proteins. In undifferentiated F9… Expand This report describes the purification and partial characterization of a novel retinoic acid-binding protein (CRABP-II) from… Expand