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CP 376395

Known as: CP-376395, CP376395 
National Institutes of Health

Papers overview

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2020
2020
Both CRF1 and CRF2 receptors in the bed nucleus of stria terminalis are involved in baroreflex impairment evoked by chronic stress in rats
2017
2017
CRF1 and CRF2 receptors in the bed nucleus of stria terminalis differently modulate the baroreflex function in unanesthetized rats
The baroreflex is an important blood pressure regulating mechanism. The bed nucleus of stria terminalis (BNST) modulates the… 
2017
2017
Rosetta Broker for membrane protein structure prediction: concentrative nucleoside transporter 3 and corticotropin-releasing factor receptor 1 test cases
BackgroundMembrane proteins are difficult targets for structure prediction due to the limited structural data deposited in… 
2017
2017
Escalated cocaine “binges” in rats: enduring effects of social defeat stress or intra-VTA CRF
Exposure to intermittent social defeat stress elicits corticotropin releasing factor (CRF) release into the VTA and induces long… 
2017
2017
CRHR1 Mediates the Up-Regulation of Synapsin I Induced by Nesfatin-1 Through ERK 1/2 Signaling in SH-SY5Y Cells
The anorexigenic molecule nesfatin-1 has recently been taken as a potential mood regulator, but the potential mechanisms remain… 
Review
2016
Review
2016
CRF and the nucleus incertus: a node for integration of stress signals
We recently read with interest the timely and scholarly Review by Henckens et al. (Regionspecific roles of the corticotropin… 
2016
2016
CRF type 1 receptor antagonism in ventral tegmental area of adolescent rats during social defeat: prevention of escalated cocaine self-administration in adulthood and behavioral adaptations during…
Activation of corticotropin-releasing factor type 1 receptors (CRF-R1) in the ventral tegmental area (VTA) represents a critical… 
2015
2015
An insight into antagonist binding and induced conformational dynamics of class B GPCR corticotropin-releasing factor receptor 1.
The human corticotropin-releasing factor receptor type 1 (CRF1R) is a class B G-protein-coupled receptor (GPCR), which mediates… 
2014
2014
Exploration of the antagonist CP-376395 escape pathway for the corticotropin-releasing factor receptor 1 by random acceleration molecular dynamics simulations.
Corticotropin-releasing factor receptor 1 (CRF1R), a member of class B G-protein-coupled receptors (GPCRs), plays an important… 
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