CIP-KIP Cyclin-Dependent Kinase Inhibitors

Known as: CIP KIP CDKI Proteins, CDKI Proteins, CIP-KIP, CIP KIP Cyclin Dependent Kinase Inhibitors 
 
National Institutes of Health

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Cyclin-Dependent Kinase Inhibitor Proteins

Papers overview

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2012
2012
Development of mice without Cip/Kip CDK inhibitors.
Timely exit of cells from the cell cycle is essential for proper cell differentiation during embryogenesis. Cyclin-dependent… (More)
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Highly Cited
2011
Highly Cited
2011
p57 is required for quiescence and maintenance of adult hematopoietic stem cells.
Quiescence is required for the maintenance of hematopoietic stem cells (HSCs). Members of the Cip/Kip family of cyclin-dependent… (More)
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Review
2009
Review
2009
Interventions for preventing critical illness polyneuropathy and critical illness myopathy.
BACKGROUND Critical illness polyneuro-and/or myopathy (CIP/CIM) is an important and frequent complication in the intensive care… (More)
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Review
2008
Review
2008
Critical illness myopathy and neuropathy.
Muscle wasting and paralysis are common complications in Intensive Care Unit (ICU) patients, where critical illness… (More)
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Highly Cited
2004
Highly Cited
2004
In vivo self-renewing divisions of haematopoietic stem cells are increased in the absence of the early G1-phase inhibitor, p18INK4C
Self-renewal of stem cells is critical for tissue repair and maintenance of organ integrity in most mammalian systems. The… (More)
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Review
2003
Review
2003
New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment?
Cell division relies on the activation of cyclins, which bind to cyclin-dependent kinases (CDKs) to induce cell-cycle progression… (More)
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2001
2001
PTEN induces G(1) cell cycle arrest and decreases cyclin D3 levels in endometrial carcinoma cells.
Inactivating mutations in the PTEN tumor suppressor gene occur in approximately 30-50% of endometrial carcinomas. PTEN is a… (More)
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Review
1998
Review
1998
Inhibitors of the Cip/Kip family.
 
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Review
1998
Review
1998
Cip/Kip cyclin-dependent kinase inhibitors: brakes of the cell cycle engine during development.
Precise control of cell-cycle progression is believed to be critical for normal development, while oncogenesis may be a direct… (More)
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1997
1997
Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-α in hematopoietic cell lines
One prominent effect of IFNs is their cell growth inhibitory activity. The exact molecular mechanism behind this inhibition of… (More)
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