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CHRM3 gene

Known as: acetylcholine receptor, muscarinic 3, CHRM3, CHOLINERGIC RECEPTOR, MUSCARINIC, 3 
This gene plays a role in the regulation of smooth muscle contraction and glandular tissue secretions.
National Institutes of Health

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7 relations
CHRM3 protein, humanCHRM3 wt AlleleG Protein-Coupled Receptor SignalingLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Chrm3 protects against acinar cell necrosis by stabilizing caspase‐8 expression in severe acute pancreatitis mice model
Acinar cells in acute pancreatitis (AP) die through apoptosis and necrosis, the impacts of which are quite different. Early… 
2019
2019
A homozygous missense variant in CHRM3 associated with familial urinary bladder disease
CHRM3 codes for the M3 muscarinic acetylcholine receptor that is located on the surface of smooth muscle cells of the detrusor… 
2018
2018
MicroRNA-30e inhibits adhesion, migration, invasion and cell cycle progression of prostate cancer cells via inhibition of the activation of the MAPK signaling pathway by downregulating CHRM3
Prostate cancer (PCa) testing is currently based on measurement of serum prostate-specific antigen levels and digital rectal… 
2016
2016
The Functional Haplotypes of CHRM3 Modulate mRNA Expression and Associate with Bladder Cancer among a Chinese Han Population in Kaohsiung City
Bladder cancer is one of the major cancer types and both environmental factors and genetic background play important roles in its… 
2014
2014
CHRM2 but not CHRM1 or CHRM3 polymorphisms are associated with asthma susceptibility in Mexican patients
Abstract Asthma is a complex disease for which genetic predisposition has been widely documented. Considerable evidence supports… 
2013
2013
Deletion 1q43 encompassing only CHRM3 in a patient with autistic disorder.
2012
2012
Muscarinic acetylcholine receptor 3 is dominant in myopia progression.
PURPOSE Numerous studies have proven that the nonselective muscarinic acetylcholine receptor (mAChR) antagonist atropine prevents… 
2011
2011
A genetic association between ß3-aderenoceptor and cholinergic receptor muscarinic 3 polymorphisms in irritable bowel syndrome.
BACKGROUND/AIMS We examined the association of ß3-adrenoceptor (ß3-AR) and cholinergic receptor muscarinic 3 (CHRM3… 
2011
2011
Potential association of muscarinic receptor 3 gene variants with primary Sjögren's syndrome
Background Primary Sjögren's syndrome (pSS) is characterised by a chronic inflammation of exocrine glands. Salivary gland… 
2003
2003
Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy.
BACKGROUND Muscarinic acetylcholine receptors are members of the superfamily of G protein-coupled, 7 transmembrane- spanning… 
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