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CHRM3 protein, human
Known as:
M3 Muscarinic Receptor
, Muscarinic Acetylcholine Receptor M3
, Cholinergic Receptor, Muscarinic 3
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Muscarinic acetylcholine receptor M3 (590 aa, ~66 kDa) is encoded by the human CHRM3 gene. This protein plays a role in both acetylcholine binding…
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National Institutes of Health
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Related topics
Related topics
13 relations
CHRM3 gene
G Protein-Coupled Receptor Genes
G Protein-Coupled Receptor Signaling
Integral Membrane Proteins
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Broader (1)
Muscarinic Acetylcholine Receptor
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Spinophilin as a novel regulator of M3 muscarinic receptor‐mediated insulin release in vitro and in vivo
I. Azúa
,
K. Nakajima
,
+4 authors
J. Wess
The FASEB Journal
2012
Corpus ID: 29917003
Spinophilin (SPL), a multidomain scaffolding protein known to modulate the activity of different G‐protein‐coupled receptors…
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2010
2010
Scopolamine Treatment and Muscarinic Receptor Subtype-3 Gene Ablation Augment Azoxymethane-Induced Murine Liver Injury
S. Khurana
,
N. Shah
,
+7 authors
J. Raufman
Journal of Pharmacology and Experimental…
2010
Corpus ID: 29380304
Previous work suggests that vagus nerve disruption reduces hepatocyte and oval cell expansion after liver injury. The role of…
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2007
2007
Ligation of Toll-Like Receptor 3 Differentially Regulates M2 and M3 Muscarinic Receptor Expression and Function in Human Airway Smooth Muscle Cells
H. Morishima
,
K. Kajiwara
,
K. Akiyama
,
Y. Yanagihara
International Archives of Allergy and Immunology
2007
Corpus ID: 2735776
Background: Viral infection causes asthma exacerbations and airway hyperreactivity. Toll-like receptor 3 (TLR3) recognizes double…
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2002
2002
Structure and transcription of the human m3 muscarinic receptor gene.
S. Forsythe
,
P. Kogut
,
+12 authors
J. Solway
American Journal of Respiratory Cell and…
2002
Corpus ID: 6280408
We have isolated and characterized the human m3 muscarinic receptor gene and its promoter. Using 5' rapid amplification of cDNA…
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2001
2001
Coincident signalling between the Gi/Go‐coupled δ‐opioid receptor and the Gq‐coupled m3 muscarinic receptor at the level of intracellular free calcium in SH‐SY5Y cells
A. Yeo
,
Damien S. K. Samways
,
C. E. Fowler
,
F. Gunn-Moore
,
Graeme Henderson
Journal of Neurochemistry
2001
Corpus ID: 2755275
In SH‐SY5Y cells, activation of δ‐opioid receptors with [d‐Pen2,5]‐enkephalin (DPDPE; 1 µm) did not alter the intracellular free…
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2001
2001
Effect of M2 and M3 muscarinic receptors on airway responsiveness to carbachol in bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs.
H. Kadota
,
M. Kuwahara
,
R. Nishibata
,
H. Mikami
,
H. Tsubone
Experimental animals
2001
Corpus ID: 19466964
The expression balance of M2 and M3 muscarinic receptor subtypes on the pathogenesis of airway hyperresponsiveness was…
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1999
1999
Use of a Sandwich Enzyme-linked Immunosorbent Assay Strategy to Study Mechanisms of G Protein-coupled Receptor Assembly*
J. Jakubík
,
J. Wess
Journal of Biological Chemistry
1999
Corpus ID: 23339112
All G protein-coupled receptors are predicted to consist of a bundle of seven transmembrane helices (I–VII) that are connected by…
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1995
1995
Stimulation of Adenylyl Cyclase Mediated by Phospholipase C‐Linked M3 Muscarinic Receptor in Human Neuroblastoma SK‐N‐BE(2)C Cells
B. Suh
,
Kyong-Tai Kim
Journal of Neurochemistry
1995
Corpus ID: 40086880
Abstract: Muscarinic receptor in human neuroblastoma SK‐N‐BE(2)C cells was identified and characterized. Treatment of the cells…
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1995
1995
Evaluation of stereoisomers of 4-fluoroalkyl analogues of 3-quinuclidinyl benzilate in in vivo competition studies for the M1, M2, and M3 muscarinic receptor subtypes in brain.
J. Lee
,
C. Paik
,
D. Kiesewetter
,
S. Park
,
W. Eckelman
Nuclear Medicine and Biology
1995
Corpus ID: 25919455
1990
1990
Inositol trisphosphate mediates cloned muscarinic receptor‐activated conductances in transfected mouse fibroblast A9 L cells.
S. Jones
,
J. Barker
,
M. Goodman
,
M. Brann
Journal of Physiology
1990
Corpus ID: 13294955
1. The mechanism by which cloned m1 and m3 muscarinic receptor subtypes activate Ca2+‐dependent channels was investigated with…
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