CHI3L1 protein, human

Known as: YKL40 protein, human, human cartilage gp39, YKL-40 protein, human 
A substance that may be found in higher-than-normal amounts in the blood of patients with certain types of cancer and inflammatory diseases. It is a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
020406019922017

Papers overview

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Highly Cited
2010
Highly Cited
2010
BACKGROUND Disease-modifying therapies for Alzheimer's disease (AD) would be most effective during the preclinical stage… (More)
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Highly Cited
2009
Highly Cited
2009
Mouse breast regression protein 39 (BRP-39; Chi3l1) and its human homologue YKL-40 are chitinase-like proteins that lack… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND The chitinase-like protein YKL-40 is involved in inflammation and tissue remodeling. We recently showed that serum YKL… (More)
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Highly Cited
2008
Highly Cited
2008
YKL-40 is a chitin-binding protein that is elevated in patients with various inflammatory conditions associated with ongoing… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The evolutionarily conserved 18-glycosyl-hydrolase family contains true chitinases and chitinase-like proteins that… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE The clinical significance of epidermal growth factor receptor variant III (EGFRvIII) expression in glioblastoma… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND/AIMS YKL-40, a mammalian member of the chitinase family, is a lectin that binds heparin and chitin. The function of… (More)
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Highly Cited
1998
Highly Cited
1998
YKL-40, also called human cartilage glycoprotein-39 (HC gp-39), is a member of family 18 glycosyl hydrolases. YKL-40 is secreted… (More)
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Highly Cited
1993
Highly Cited
1993
One of the major secreted proteins of human articular chondrocytes in monolayer or explant culture and of synovial fibroblasts is… (More)
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Highly Cited
1993
Highly Cited
1993
We report the development of the first radioimmunoassay for YKL-40, a M(r) = 40 kDa protein which is secreted at high levels by… (More)
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