High serum YKL-40 level in patients with small cell lung cancer is related to early death.

@article{Johansen2004HighSY,
  title={High serum YKL-40 level in patients with small cell lung cancer is related to early death.},
  author={Julia Sidenius Johansen and Lars B Drivsholm and Paul A. Price and Ib Jarle Christensen},
  journal={Lung cancer},
  year={2004},
  volume={46 3},
  pages={333-40}
}
YKL-40, a growth factor for connective tissue cells, is secreted by cancer cells and macrophages. Elevated serum YKL-40 in patients with metastatic carcinoma has been associated with poor prognosis. We evaluated serum YKL-40 in 131 patients with small cell lung cancer (SCLC). Twenty-two percent of the patients with limited disease and 40% of the patients with extensive disease had elevated serum YKL-40. The median survival was 5.1 months for patients with elevated serum YKL-40 and 9.0 months… CONTINUE READING

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High serum YKL-40 levels in patients with primary breast cancer is related to short recurrence free interval. Breast Cancer Res Treat 2003;80:15—21

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