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CGS 13080

Known as: CGS-13080 
 
National Institutes of Health

Papers overview

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Highly Cited
1995
Highly Cited
1995
To test the role of reactive oxygen species and cyclooxygenase products in the retinal hemodynamic changes induced by asphyxia… Expand
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Highly Cited
1993
Highly Cited
1993
Vascular relaxations are impaired in adult spontaneously hypertensive rats (SHRs) because of increased production of an… Expand
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Highly Cited
1991
Highly Cited
1991
The endothelium releases substances controlling vascular tone and platelet function. We investigated mediators of endothelium… Expand
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1989
1989
1 Administration of arachidonic acid caused dose‐dependent vasoconstriction in the isolated rat kidney perfused in situ with… Expand
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1987
1987
The focus of this investigation was to examine the potential beneficial effects of the selective thromboxane synthetase inhibitor… Expand
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1985
1985
Increase in thromboxane A2 (TXA2) generation has been proposed as a mechanism of dynamic vaso-occlusion and in vivo platelet… Expand
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1984
1984
Abstract: CGS‐13080 is a new potent selective inhibitor of thromboxane synthetase. This study reports the results of a safety and… Expand
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Highly Cited
1984
Highly Cited
1984
1 Platelet activating factor (Paf) (15–40 μg−1) kills male rabbits within 3 to 5 min. Intravenous injection of Paf at a dose of… Expand
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1983
1983
CGS 13080 inhibited cell-free thromboxane synthetase with an IC50 of 3 nM. It was at least five orders of magnitude less potent… Expand
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1983
1983
A specific inhibitor of thromboxane A2 (TxA2) synthesis, CGS-13080, was studied during acute myocardial ischemia (MI) in cats. To… Expand
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