CERS5 gene

Known as: LASS5, MGC45411, Trh4 
This gene is involved in ceramide synthesis and cell signaling.
National Institutes of Health

Topic mentions per year

Topic mentions per year

2003-2018
02420032018

Papers overview

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2016
2016
Tumor cells frequently escape from CD8+ T cell recognition by abrogating MHC-I antigen presentation. Deficiency in processing… (More)
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2012
2012
Ceramide, the backbone of all sphingolipids, is synthesized by a family of ceramide synthases (CerS) that each use acyl-CoAs of… (More)
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2012
2012
In mammals, ceramides are synthesized by a family of six ceramide synthases (CerS), transmembrane proteins located in the… (More)
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2011
2011
The sphingolipid ceramide has been widely implicated in the regulation of programmed cell death or apoptosis. The accumulation of… (More)
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2007
2007
Synthesis of VLCFAs (very long chain fatty acids) and biosynthesis of DHS (dihydrosphingosine) both are of vital importance for… (More)
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2006
2006
Lag1 (longevity assurance gene 1) homologues, a family of transmembrane proteins found in all eukaryotes, have been shown to be… (More)
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Highly Cited
2005
Highly Cited
2005
The Lass (longevity-assurance homologue) family members, which are highly conserved among eukaryotes, function in ceramide… (More)
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2005
2005
We demonstrated recently (Riebeling, C., Allegood, J.C., Wang, E., Merrill, A. H. Jr., and Futerman, A. H. (2003) J. Biol. Chem… (More)
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2005
2005
Ceramide is a key bioactive mediator that inhibits surfactant phosphatidylcholine (PtdCho) synthesis in lung epithelia. Ceramide… (More)
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Highly Cited
2003
Highly Cited
2003
Overexpression of upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance… (More)
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