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CERS5 gene

Known as: LASS5, MGC45411, TRH4 
This gene is involved in ceramide synthesis and cell signaling.
National Institutes of Health

Papers overview

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2019
2019
Ectopic lipid deposition and altered mitochondrial dynamics contribute to the development of obesity and insulin resistance… Expand
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2018
2018
Resistance against chemotherapy is a life-threatening complication in colon cancer therapy. To increase response rate, new… Expand
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2017
2017
Cystic fibrosis is the most common genetic disease, in which symptoms may be alleviated but not fully eliminated. Ceramides have… Expand
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2016
2016
MHC class I downregulation represents a significant challenge for successful T cell–based immunotherapy. T cell epitopes… Expand
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2014
2014
Ceramide synthases (CerS) are important enzymes of the sphingolipid pathway, responsible for the production of ceramides with… Expand
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Highly Cited
2006
Highly Cited
2006
A new variant of a group of pediatric neurodegenerative diseases known as neuronal ceroid lipofuscinosis (NCL) or Batten disease… Expand
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Highly Cited
2006
Highly Cited
2006
Lag1 (longevity assurance gene 1) homologues, a family of transmembrane proteins found in all eukaryotes, have been shown to be… Expand
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Highly Cited
2006
Highly Cited
2006
Defects in major histocompatibility complex (MHC) class I–restricted antigen presentation are frequently observed in human… Expand
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Highly Cited
2005
Highly Cited
2005
We demonstrated recently (Riebeling, C., Allegood, J.C., Wang, E., Merrill, A. H. Jr., and Futerman, A. H. (2003) J. Biol. Chem… Expand
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Highly Cited
2003
Highly Cited
2003
Overexpression of upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance… Expand
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