Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

CERS5 protein, human

Known as: longevity assurance gene homolog 5, human, LAG1 Longevity Assurance Homolog 5 (S. cerevisiae), ceramide synthetase 5, human 
Ceramide synthase 5 (392 aa, ~46 kDa) is encoded by the human CERS5 gene. This protein is involved in apoptosis via the mitochondrial death pathway.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Impaired mitochondrial maintenance in disparate cell types is a shared hallmark of many human pathologies and ageing. How… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2014
Highly Cited
2014
The purpose of these guidelines is to assist physicians in recommending, performing, interpreting and reporting the results of… Expand
  • table 1
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Reduced insulin/IGF signaling extends lifespan in diverse species, including Drosophila melanogaster where the genome encodes… Expand
Is this relevant?
Highly Cited
2011
Highly Cited
2011
The sphingolipid ceramide has been widely implicated in the regulation of programmed cell death or apoptosis. The accumulation of… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2010
Highly Cited
2010
The role of ceramide neo-genesis in cellular stress response signaling is gaining increasing attention with recent progress in… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
Several in vitro studies have correlated dysfunction of the sphingolipid-signaling pathway with promotion of tumor cell growth as… Expand
  • figure 1
  • figure 2
  • figure 3
  • table I
  • figure 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
In this study, quantitative isobologram studies showed that treatment with gemcitabine and doxorubicin, known inducers of… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
BackgroundTo what extent are the determinants of aging in animal species universal? Insulin/insulin-like growth factor (IGF)-1… Expand
  • table 1
  • table 2
  • table 3
  • table 4
  • table 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
The LASS (longevity assurance homologue) family members are highly conserved from yeasts to mammals. Five mouse and human LASS… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
This paper provides empirical evidence on the economic value of services provided by independent auditors by analyzing whether… Expand
Is this relevant?