CER-001
National Institutes of Health
Papers overview
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BACKGROUND
High-density lipoprotein (HDL) is believed to have atheroprotective properties, but an effective HDL-based therapy…
BACKGROUND
CER-001 is an engineered pre-beta high-density lipoprotein (HDL) mimetic, which rapidly mobilizes cholesterol…
The incidence of CHD is still increasing, which underscores the need for new preventive and therapeutic approaches to decrease…
Objective CER-001 is a novel engineered HDL-mimetic comprised of recombinant human apoA-I and charged phospholipids that was…
Clinical intervention studies have provided clear evidence that low‐density lipoproteins are causally involved in the development…
Cardiovascular disease remains the most pressing healthcare issue for the developed world and is becoming so for developing…
Introduction: Infusing high-density lipoprotein (HDL) has been shown to promote plaque regression in patients with acute coronary…
Background Reverse cholesterol transport (RCT) contributes to the anti-atherogenic effects of High-density lipoprotein (HDL…
This editorial refers to ‘Effects of the high-density lipoprotein mimetic agent CER-001 on coronary atherosclerosis in patients…
Background: CER-001 is a synthetic HDL, comprised of recombinant human ApoA-I complexed with phospholipids and designed to mimic…