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CEN-209

National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Cyclic N-OxidesTriazines

Narrower (1)

SN30000

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Imaging Tumor Sensitivity to a Bioreductive Prodrug: Two for the Price of One!
Hypoxia is an important characteristic of many solid tumors and has a major negative effect on treatment response. A way to… 
2012
2012
Introducing Drug Transport Early in the Design of Hypoxia Selective Anticancer Agents Using a Mathematical Modelling Approach
Hypoxia is more severe in tumors than normal tissues, and contributes to tumor progression and therapeutic resistance. It is… 
2011
2011
EF5 as a predictive biomarker for activation of the new hypoxia-targeting prodrug SN30000.
e13597 Background: SN30000 (CEN-209), a benzotriazine-N-oxide, is a second generation analogue of tirapazamine (TPZ) and is… 
2011
2011
Abstract 5306: 18F-EF5 microPET imaging of treatment response from a novel, hypoxia-selective cytotoxin SN30000 in a human lung cancer xenograft model
Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL Introduction: SN30000 (CEN-209) is a structural… 
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