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CDS-E2
Known as:
E2-CDS
National Institutes of Health
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Papers overview
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Highly Cited
1997
Highly Cited
1997
17 β-Estradiol Attenuates Fimbrial Lesion-Induced Decline of ChAT-Immunoreactive Neurons in the Rat Medial Septum
O. Rabbani
,
K. Panickar
,
+4 authors
J. Simpkins
Experimental Neurology
1997
Corpus ID: 24023138
We investigated the neuroprotective effects of 17 beta-estradiol (E2) on medial septal cholinergic neurons following partial…
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1996
1996
Intravenous and Buccal 2-Hydroxypropyl-β-Cyclodextrin Formulations of E2-CDS — Phase I Clinical Trials
M. Brewster
,
J. Howes
,
+4 authors
E. Pop
1996
Corpus ID: 68317395
Intravenous and buccal dosage forms were configured for E2-CDS, a brain-targeting estrogen delivery system, using 2-hydroxypropyl…
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1991
1991
Effects of a brain-enhanced estrogen delivery system on tail-skin temperature of the rat: implications for menopausal hot flush.
M. Rahimy
,
N. Bodor
,
J. Simpkins
Maturitas
1991
Corpus ID: 33917356
1991
1991
The effects of a brain-enhanced estradiol delivery system on testosterone and androgen-dependent tissues. I. Dose-response and time-course evaluation.
M. Rahimy
,
W. Anderson
,
M. Brewster
,
N. Bodor
,
J. Simpkins
Endocrinology
1991
Corpus ID: 22409536
The primary objective underlying hormone treatment of prostatic adenocarcinoma is to induce an effective androgen deprivation…
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1990
1990
The role of conditioned taste aversion in the suppression of food intake by estradiol
R. Ganesan
,
J. Simpkins
Physiology and Behavior
1990
Corpus ID: 8904364
1990
1990
A Redox-Based System that Enhances Delivery of Estradiol to the Brain: Pharmacokinetic Evaluation in the Dog
K. Dietzel
,
V. Keuth
,
+5 authors
H. Derendorf
Pharmaceutical Research
1990
Corpus ID: 23114376
The pharmacokinetics of a dihydropyridine–pyridinium salt-type chemical delivery system (CDS) for brain-targeted delivery of…
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1990
1990
Dose and Time-Course Evaluation of a Redox-Based Estradiol-Chemical Delivery System for the Brain. I. Tissue Distribution
M. Rahimy
,
J. Simpkins
,
N. Bodor
Pharmaceutical Research
1990
Corpus ID: 5975010
AbstractBrain-enhanced delivery and sustained release of estradiol (E2) may be potentially useful in the treatments of vasomotor…
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1989
1989
Effects of a Brain-Enhanced Chemical Delivery System for Estradiol on Body Weight and Food Intake in Intact and Ovariectomized Rats
J. Simpkins
,
W. Anderson
,
R. Dawson
,
N. Bodor
Pharmaceutical Research
1989
Corpus ID: 23336912
Studies were undertaken to determine the effects on body weight of a brain-enhanced chemical delivery system for estradiol. This…
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1988
1988
Evidence for suppression of serum LH without elevation in serum estradiol or prolactin with a brain-enhanced redox delivery system for estradiol.
W. Anderson
,
J. Simpkins
,
M. Brewster
,
N. Bodor
Life Science
1988
Corpus ID: 24887993
1987
1987
Evidence for the reestablishment of copulatory behavior in castrated male rats with a brain-enhanced estradiol-chemical delivery system
W. Anderson
,
J. Simpkins
,
M. Brewster
,
N. Bodor
Pharmacology, Biochemistry and Behavior
1987
Corpus ID: 10907814
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