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CDKN3 gene

Known as: CDI1, CYCLIN-DEPENDENT KINASE INHIBITOR 3, kinase associated phosphatase 
This gene plays a role in cell cycle regulation.
National Institutes of Health

Related topics

Related topics

9 relations
Beckwith-Wiedemann SyndromeCDKN3 protein, humanCell Cycle ControlCyclin-Dependent Kinase Inhibitor Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
NFI‐A disrupts myeloid cell differentiation and maturation in septic mice
Mounting evidence supports that sepsis‐associated immunosuppression increases mortality. As potential contributors to poor sepsis… 
2015
2015
Mechanistic studies of cyclin-dependent kinase inhibitor 3 (CDKN3) in colorectal cancer.
Colorectal cancer is one of the most severe subtypes of cancer, and has the highest propensity to manifest as metastatic disease… 
Highly Cited
2007
Highly Cited
2007
In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma
Kruppel-like factor (KLF) 6 is a tumor-suppressor gene functionally inactivated by loss of heterozygosity, somatic mutation and… 
2004
2004
A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.
Highly Cited
2003
Highly Cited
2003
Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme.
2000
2000
Differential role for Sp1/Sp3 transcription factors in the regulation of the promoter activity of multiple cyclin‐dependent kinase inhibitor genes
Cyclin‐dependent kinase inhibitors play a significant role in cell cycle progression and in cellular differentiation and their… 
Highly Cited
1998
Highly Cited
1998
Constitutive Expression of the Cyclin-dependent Kinase Inhibitor p21 Is Transcriptionally Regulated by the Tumor Suppressor Protein p53*
The tumor suppressor protein p53 has been implicated in the response of cells to DNA damage. Studies to date have demonstrated a… 
1998
1998
Screening of germline mutations in the CDK4, CDKN2C and TP53 genes in familial melanoma: a clinic-based population study.
Germline mutations within the CDKN2A gene, coding for the cyclin-dependent kinase inhibitor p16, have been detected by screening… 
1997
1997
Lack of imprinting of three human cyclin-dependent kinase inhibitor genes.
Genomic imprinting is an epigenetic modification in the germline leading to parental allele-specific gene expression in somatic… 
1988
1988
Antigen recognition by human T cell receptor gamma-positive lymphocytes. Specific lysis of allogeneic cells after activation in mixed lymphocyte culture
These experiments were designed to define the ability of human TCR- gamma+ cells to recognize allogeneic cells. TCR-gamma… 
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