CDKN2B gene

Known as: TP15, p15INK4b, cyclin-dependent kinase inhibitor 2B (CDKN2B) gene 
This gene is involved in cell cycle regulation and arrest.
National Institutes of Health

Papers overview

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2012
2012
BACKGROUND To date, only a small portion of the genetic variation for primary open-angle glaucoma (POAG), the major type of… (More)
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2012
2012
The programmed cell death-1 (PD)-1 receptor (CD279) is a potent T cell inhibitor with a critical role in peripheral tolerance… (More)
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Highly Cited
2011
Highly Cited
2011
A 42 kb region on human chromosome 9p21 encodes for three distinct tumor suppressors, p16INK4A, p14ARF and p15INK4B, and is… (More)
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Highly Cited
2009
Highly Cited
2009
OBJECTIVE In recent genome-wide association studies, variants in CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, CDKN2B, LOC387761, and FTO… (More)
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2004
2004
PURPOSE Aberrant methylation of 5' gene promoter regions is an epigenetic phenomenon that is a major mechanism for silencing of… (More)
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2000
2000
The serum concentration of transforming growth factor beta (TGF-beta) is elevated as tumors progress in hepatocellular carcinoma… (More)
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Highly Cited
1999
Highly Cited
1999
Densely methylated DNA associates with transcriptionally repressive chromatin characterized by the presence of underacetylated… (More)
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1997
1997
BACKGROUND Approximately 10% of human cutaneous melanomas occur in families in which several members are affected. The familial… (More)
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Highly Cited
1997
Highly Cited
1997
Previous studies have shown that the cyclin-dependent kinase inhibitor (CDKI) genes p15INK4B and p16INK4A are frequently… (More)
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Highly Cited
1994
Highly Cited
1994
Transforming growth factor-beta (TGF-beta) inhibits cell proliferation by inducing a G1-phase cell cycle arrest. Normal… (More)
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