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CDKN1B gene

Known as: CYCLIN-DEPENDENT KINASE INHIBITOR 1B, Cyclin Dependent Kinase Inhibitor 1B Gene, P27KIP1 
This gene is involved in cell cycle regulation and cyclin regulation.
National Institutes of Health

Related topics

Related topics

4 relations
Beckwith-Wiedemann SyndromeCell Cycle Controlcyclin-dependent kinase inhibitor 1B

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CDKN1B wt Allele

Papers overview

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2009
2009
Sequestration of E12/E47 and suppression of p27KIP1 play a role in Id2-induced proliferation and tumorigenesis.
Id2 is a member of the helix-loop-helix (HLH) family of transcription regulators known to antagonize basic HLH transcription… 
2008
2008
Expression of senescence-related genes in human corneal endothelial cells
Purpose To investigate the expression of p16INK4a, p21WAF1/CIP1, p27KIP1, and p53 in human corneal endothelial cell (HCEC… 
2007
2007
Genetic screening reveals an essential role of p27kip1 in restriction of breast cancer progression.
The genetic changes and mechanisms underlying the progression of estrogen-dependent breast cancers to estrogen-independent… 
2007
2007
In vitro differentiation of HT‐29 M6 mucus‐secreting colon cancer cells involves a trychostatin A and p27KIP1‐inducible transcriptional program of gene expression
Tumor cell dedifferentiation—such as the loss of cell‐to‐cell adhesion in epithelial tumors—is associated with tumor progression… 
2004
2004
Involvement of p27(KIP1) in proliferation of the retinal pigment epithelium and ciliary body
According to observations in various cell lines, elimination of the cyclin-dependent kinase inhibitor p27(KIP1) during the late… 
2003
2003
The inhibition of Ras farnesylation leads to an increase in p27Kip1 and G1 cell cycle arrest.
HR12 is a novel farnesyltransferase inhibitor (FTI). We have shown previously that HR12 induces phenotypic reversion of H-rasV12… 
Highly Cited
2003
Highly Cited
2003
Skp2 and Jab1 Expression Are Associated with Inverse Expression of p27KIP1 and Poor Prognosis in Oral Squamous Cell Carcinomas
Previous studies have shown that low levels of p27KIP1, an inhibitor of G1 cyclin-dependent kinases (CDK), are associated with… 
2001
2001
Expression of p27(KIP1) and p21(WAF1/CIP1) in primary hepatocellular carcinoma: clinicopathologic correlation and survival analysis.
To investigate the possible roles of p27(KIP1) and p21(WAF1/CIP1), inhibitors of cyclin-dependent kinases, in hepatocellular… 
2000
2000
Expression of cyclin E and p27(KIP1) in cervical carcinoma.
Carcinogenesis is characterized by deregulation of the cell cycle. Although p53 is still the most important cell-cycle regulator… 
1997
1997
Biological activity of p27kip1 and its amino- and carboxy-terminal domains in G2/M transition of Xenopus oocytes
p27kip1 is a general inhibitor of Cdks that preferentially accumulates and functions during G1 phase, before the restriction… 
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