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CDKN1B wt Allele

Known as: Cyclin Dependent Kinase Inhibitor 1B wt Allele, P27KIP1, Kip1 
Human CDKN1B wild-type allele is located within 12p13.1-p12 and is approximately 5 kb in length. This allele, which encodes cyclin-dependent kinase… 
National Institutes of Health

Related topics

Related topics

6 relations
Beckwith-Wiedemann SyndromeCTCF PathwayCell Cycle ControlG1/S Checkpoint Pathway

Broader (1)

CDKN1B gene

Papers overview

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2006
2006
Tyrosine phosphorylation modulates binding preference to cyclin-dependent kinases and subcellular localization of p27Kip1 in the acute promyelocytic leukemia cell line NB4.
We have investigated the role of tyrosine phosphorylation of the cyclin-dependent kinase (cdk) inhibitor p27Kip1 using the acute… 
2004
2004
Decreased expression of the CDK inhibitor p27Kip1 and increased oxidative DNA damage in the multistep process of cervical carcinogenesis.
2003
2003
p27Kip1 is an independent predictor of recurrence after surgical resection in patients with small hepatocellular carcinoma
2003
2003
Effect of p27Kip1 on the ability of invasion and metastasis of an oral cancer cell line.
p27Kip1 is a cyclin-dependent kinase inhibitor which regulates progression of cells from G1 into S phase in a cell cycle. p27Kip1… 
2000
2000
Loss of p27Kip1 expression is a strong independent prognostic factor of reduced survival in N0 gastric carcinomas
p27Kip1 is a cyclin‐dependent kinase inhibitor and is a potential tumor suppressor gene. Reduced expression of p27Kip1 is a… 
2000
2000
Differentiation-associated expression and intracellular localization of cyclin-dependent kinase inhibitor p27KIP1 and c-Jun co-activator JAB1 in neuroblastoma.
Neuroblastoma is a unique pediatric cancer, which spontaneously regress in some infants and undergo maturation in older children… 
2000
2000
Loss of p27KIP1 Expression Predicts Poor Prognosis in Patients with Esophageal Squamous Cell Carcinoma
Immunohistochemical studies of cell cycle-regulating proteins were conducted on tissue samples from 106 patients with esophageal… 
2000
2000
p27Kip1 loss does not predict survival in patients with advanced gastric carcinoma
p27Kip1 is a cyclin‐dependent kinase inhibitor whose loss is associated with disease progression and an unfavorable outcome in… 
1999
1999
Reduced expression of p27Kip1 protein is associated with poor clinical outcome of breast cancer patients treated with systemic chemotherapy and is linked to cell proliferation and differentiation
The cyclin‐dependent kinase inhibitor p27Kip1 is a negative regulator of cell proliferation. Its expression is known to be… 
1996
1996
Paradoxical accumulation of the cyclin-dependent kinase inhibitor p27kip1 during the cAMP-dependent mitogenic stimulation of thyroid epithelial cells.
In different systems, cAMP either blocks or promotes cell cycle progression in mid to late G1 phase. Dog thyroid epithelial cells… 
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