CDKN1B wt Allele

Known as: Cyclin Dependent Kinase Inhibitor 1B wt Allele, P27KIP1, Kip1 
Human CDKN1B wild-type allele is located within 12p13.1-p12 and is approximately 5 kb in length. This allele, which encodes cyclin-dependent kinase… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The naked mole-rat is the longest living rodent with a maximum lifespan exceeding 28 years. In addition to its longevity, naked… (More)
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Highly Cited
2005
Highly Cited
2005
The protein p27Kip1 regulates cell cycle progression in mammals by inhibiting the activity of cyclin-dependent kinases (CDKs… (More)
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Highly Cited
2000
Highly Cited
2000
A senescence-like growth arrest is induced in mouse primary embryo fibroblasts by inhibitors of phosphoinositide 3-kinase (PI3K… (More)
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Highly Cited
1999
Highly Cited
1999
Although the significance of vascular endothelial growth factor (VEGF) and its receptors in angiogenesis is well established, the… (More)
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Highly Cited
1998
Highly Cited
1998
The molecular mechanism of androgen-independent growth of prostate cancer after androgen ablation was explored in LNCaP cells. An… (More)
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Highly Cited
1998
Highly Cited
1998
p27Kip is a candidate human tumour-suppressor protein, because it is able to inhibit cyclin-dependent kinases and block cell… (More)
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Highly Cited
1997
Highly Cited
1997
Breast cancer is the second leading cause of cancer death in North American women. There is considerable need for reliable… (More)
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Highly Cited
1997
Highly Cited
1997
p27Kip1, a member of the Cip/Kip family of cyclin-dependent kinase (cdk) inhibitors, has been implicated in mediating G1 arrest… (More)
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Highly Cited
1997
Highly Cited
1997
p27Kip1, a cyclin-dependent kinase inhibitor, is recognized as a negative regulator of the cell cycle. In this paper, we report… (More)
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Highly Cited
1996
Highly Cited
1996
Cell cycle phase transitions in eukaryotic cells are driven by regulation of the activity of protein kinases known as cyclin… (More)
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