cyclin-dependent kinase inhibitor 1B

Known as: Cyclin Dependent Kinase Inhibitor 1B, CDK Inhibitor p27, p27 CDK Inhibitor 
A cyclin-dependent kinase inhibitor that coordinates the activation of CYCLIN and CYCLIN-DEPENDENT KINASES during the CELL CYCLE. It interacts with… (More)
National Institutes of Health

Papers overview

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2013
2013
Dysregulation of miR-452 has been observed in many tumors, but its biological function in hepatocellular carcinoma (HCC) is still… (More)
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Highly Cited
2002
Highly Cited
2002
The F-box protein Skp2 (Fbl1) is a positive regulator of G1-S transition and promotes ubiquitin-mediated proteolysis of the… (More)
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Highly Cited
2001
Highly Cited
2001
Upon engagement of the B Cell Receptor (BCR) of WEHI 231 immature B cells, a drop in c-Myc expression is followed by activation… (More)
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Highly Cited
1999
Highly Cited
1999
The proliferation of mammalian cells is under strict control, and the cyclin-dependent-kinase inhibitory protein p27Kip1 is an… (More)
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Highly Cited
1998
Highly Cited
1998
Arterial lesions in cardiovascular diseases are characterized by proliferation and migration of smooth muscle cells as well as… (More)
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Highly Cited
1998
Highly Cited
1998
A constitutively active form of mitogen-activated protein kinase kinase (MEK1) was synthesized under control of a zinc-inducible… (More)
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Highly Cited
1996
Highly Cited
1996
SUMMARY Disruption of the cyclin-dependent kinase-inhibitory domain of p27 enhances growth of mice. Growth is attributed to an… (More)
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Highly Cited
1996
Highly Cited
1996
The crystal structure of the human p27Kip1 kinase inhibitory domain bound to the phosphorylated cyclin A–cyclin-dependent kinase… (More)
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Highly Cited
1995
Highly Cited
1995
The p27 mammalian cell cycle protein is an inhibitor of cyclin-dependent kinases. Both in vivo and in vitro, p27 was found to be… (More)
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Highly Cited
1994
Highly Cited
1994
We cloned p27Kip1, a cyclin-dependent kinase inhibitor implicated in G1 phase arrest by TGF beta and cell-cell contact. p27Kip1… (More)
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