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CDK1 wt Allele

Known as: P34CDC2, p34 Protein Kinase Gene, Cell Division Cycle 2 Protein Gene 
Human CDK1 wild-type allele is located in the vicinity of 10q21.1 and is approximately 61 kb in length. This allele, which encodes cyclin-dependent… Expand
National Institutes of Health

Papers overview

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Highly Cited
1997
Highly Cited
1997
We describe a novel gene targeting strategy for the genetic analysis of essential genes in mammalian cells and its use to study… Expand
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Highly Cited
1996
Highly Cited
1996
The induction of tumor cell death by anticancer therapy results from a genetic program of autonomous cell death termed apoptosis… Expand
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Highly Cited
1992
Highly Cited
1992
Phosphorylation of p34cdc2 can both positively and negatively regulate its kinase activity. We have mapped two phosphorylation… Expand
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Highly Cited
1992
Highly Cited
1992
M phase promoting factor (MPF) is a major element controlling entry into the M phase of the eukaryotic cell cycle. MPF is… Expand
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Highly Cited
1992
Highly Cited
1992
In human epidermal carcinoma A431 cells, the beta subunit of casein kinase II is phosphorylated at an autophosphorylation site… Expand
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Highly Cited
1991
Highly Cited
1991
Mutants of cdc2+ can disrupt the dependency of S phase on completion of the previous mitosis. By changing the state of p34cdc2 it… Expand
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Highly Cited
1991
Highly Cited
1991
p34cdc2 protein kinase is a universal regulator of M-phase in eukaryotic cell cycle. To investigate the regulation of meiotic and… Expand
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Highly Cited
1991
Highly Cited
1991
A universal intracellular factor, the ‘M phase‐promoting factor’ (MPF), triggers the G2/M transition of the cell cycle in all… Expand
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Highly Cited
1989
Highly Cited
1989
The cdc2+ gene product p34cdc2 is located immunocytochemically in both the nucleus and cytoplasm of human cells. It is uniformly… Expand
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Highly Cited
1987
Highly Cited
1987
cdc2+ encodes a protein kinase that is required during both G1 and G2 phases of the cell division cycle in fission yeast. suc1… Expand
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