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CDC7 gene

Known as: CDC7L1, HsCdc7, cell division cycle 7 
This gene is involved in the initiation of DNA replication and inhibition of cell proliferation. It also plays a putative role in the mediation of… 
National Institutes of Health

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CDC7 protein, humanDNA ReplicationReplication Initiation

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CDC7 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Targeting CDC7 improves sensitivity to chemotherapy of esophageal squamous cell carcinoma
Purpose The cell division cycle 7 (CDC7) is a serine/threonine kinase that is essential for DNA replication in human cells which… 
2016
2016
Cell division cycle 7-kinase inhibitor PHA-767491 hydrochloride suppresses glioblastoma growth and invasiveness
BackgroundGenomic instability is a hallmark of cancer cells, and this cellular phenomenon can emerge as a result of replicative… 
2014
2014
Characterization of a Drosophila Ortholog of the Cdc7 Kinase
Background: Cdc7 is a kinase that, together with its activator Dbf4, regulates the initiation of DNA replication. Results… 
2013
2013
Biological Activities of Phosphocitrate: A Potential Meniscal Protective Agent
Phosphocitrate (PC) inhibited meniscal calcification and the development of calcium crystal-associated osteoarthritis (OA) in… 
2013
2013
Expression of huCdc7 in colorectal cancer.
AIM To detect the expression of huCdc7 in colorectal cancer. METHODS The mRNA and protein expression of huCdc7 in 39 colorectal… 
2013
2013
Preclinical research in treatment of pancreatic cancer.
Pancreatic adenocarcinoma is an aggressive type of malignancy and remains a treatment-refractory cancer. Because of the few… 
2011
2011
Linkage and association analyses of glaucoma related traits in a large pedigree from a Dutch genetically isolated population
Background Despite extensive research on the genetic determinants of glaucoma, the genes identified to date explain only a small… 
1999
1999
Cloning and Characterization of Chinese Hamster CDC7 (ChCDC7)
The Cdc7 serine/threonine kinase is essential for entry into and to traverse through S phase. We have cloned the putative Chinese… 
Highly Cited
1988
Highly Cited
1988
Differential regulation of the yeast CDC7 gene during mitosis and meiosis
The product of the CDC7 gene of Saccharomyces cerevisiae is known to be required in the mitotic cell cycle for the initiation of… 
1988
1988
CDC7-dependent protein kinase activity in yeast replicative-complex preparations.
A protein kinase activity was identified in preparations of DNA-replicative complex from the budding yeast Saccharomyces… 
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