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CDC45L protein, human

Known as: Cell Division Cycle 45, S. cerevisiae, Homolog-Like, CDC45-Like, CDC45 Cell Division Cycle 45-Like (S. cerevisiae) 
CDC45-related protein (566 aa, ~66 kDa) is encoded by the human CDC45L gene. This protein is involved in the initiation of genomic DNA replication.
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
BackgroundInducible inactivation of a protein is a powerful approach for analysis of its function within cells. Fission yeast is… Expand
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Highly Cited
2007
Highly Cited
2007
In eukaryotic cells, cyclin-dependent kinases (CDKs) have an important involvement at various points in the cell cycle. At the… Expand
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2007
2007
Cdc45 is an essential cellular protein that functions in both the initiation and elongation of DNA replication. Here, we analyzed… Expand
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Highly Cited
2005
Highly Cited
2005
Cdc45 is required for initiation of DNA replication and fork progression, but its function in these processes remains unknown. We… Expand
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Highly Cited
2003
Highly Cited
2003
We have identified Xenopus homologs of the budding yeast Sld5 and its three interacting proteins. These form a novel complex… Expand
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Highly Cited
2003
Highly Cited
2003
Using a cytological assay to monitor the successive chromatin association of replication proteins leading to replication… Expand
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Highly Cited
2002
Highly Cited
2002
The initiation of eukaryotic DNA replication involves origin recruitment and activation of the MCM2-7 complex, the putative… Expand
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Highly Cited
2000
Highly Cited
2000
BACKGROUND In eukaryotes, chromosomal DNA is licensed to be replicated through the sequential loading of the origin recognition… Expand
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Highly Cited
2000
Highly Cited
2000
The notochord has two major roles during chordate embryogenesis, as a source of inductive signals for the patterning of neural… Expand
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1997
1997
The initiation of DNA replication in Saccharomyces cerevisiae requires the protein product of the CDC45 gene. We report that… Expand
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