CDB 2914

OBJECTIVE To test potential contraceptive mechanisms of the selective P receptor modulator CDB-2914 in the early luteal phase… (More)

BACKGROUND Ulipristal (UPA; CDB-2914) is a progesterone receptor modulator with contraceptive potential. To test its effects when… (More)

CONTEXT Progesterone is critical for secretory endometrial differentiation in women, but its downstream mediators are poorly… (More)

OBJECTIVE To evaluate whether 3-month administration of CDB-2914, a selective progesterone receptor modulator, reduces leiomyoma… (More)

Effects of progesterone receptor modulator CDB-2914 on the expression of the extracellular matrix (ECM) components were examined… (More)

BACKGROUND This study was conducted to evaluate the effects of graded concentrations (10(-8), 10(-7) and 10(-6) M) of… (More)

In determining the biological profiles of various antiprogestins, it is important to assess the hormonal and antihormonal… (More)

CDB-2914 (17 alpha-acetoxy-11 beta-[4-N,N-dimethylaminophenyl]-19-norpregna-4,9-diene-3,20-dione) is a 19-norprogesterone… (More)

To obtain selective antiprogestins, we have examined the in vitro antiprogestational/antiglucocorticoid properties of two novel… (More)

Our goal was to determine the endocrine and post-coital anti-fertility activity of CDB-2914. Concurrent administration of… (More)