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CD70 gene

Known as: CD70 ANTIGEN, CD70 Molecule Gene, CD27L 
This gene is involved in immune function.
National Institutes of Health

Related topics

Related topics

9 relations
CD70 AntigenCell DeathCell Proliferation Regulatory ProcessCytokine Receptor Binding

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CD70 wt Allele

Papers overview

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Highly Cited
2011
Highly Cited
2011
Cutting Edge: Virus Selectively Primes Human Langerhans Cells for CD70 Expression Promoting CD8+ T Cell Responses
The two outermost compartments of skin are populated by different Ag-presenting dendritic cell types. Epidermal Langerhans cells… 
2011
2011
CD70 is selectively expressed on Th1 but not on Th2 cells and is required for Th1-type immune responses.
The interaction between CD27 and CD70 provides a costimulatory signal for T-cell survival. Although the role of CD27 signaling in… 
2010
2010
Soluble CD70: a novel immunotherapeutic agent for experimental glioblastoma.
OBJECT Given the overall poor outcome with current treatment strategies in malignant gliomas, immunotherapy has been considered a… 
2010
2010
Demethylation of promoter regulatory elements contributes to CD70 overexpression in CD4+ T cells from patients with subacute cutaneous lupus erythematosus
Background.  Impaired methylation of T‐cell DNA is thought to contribute to the development of systemic lupus erythematosus (SLE… 
2006
2006
Host Response to the Attenuated Poxvirus Vector NYVAC: Upregulation of Apoptotic Genes and NF-κB-Responsive Genes in Infected HeLa Cells
ABSTRACT NYVAC has been engineered as a safe, attenuated vaccinia virus (VV) vector for use in vaccination against a broad… 
Highly Cited
2000
Highly Cited
2000
Involvement of CD70–CD27 interactions in the induction of experimental autoimmune encephalomyelitis
2000
2000
The expression of CD70 and CD80 by gene-modified tumor cells induces an antitumor response depending on the MHC status
The expression of costimulatory molecules such as CD70 or CD80 by gene-modified tumor cells has been shown to enhance the… 
Highly Cited
1998
Highly Cited
1998
Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells.
CD70 (CD27 ligand (CD27L)), CD153 (CD30L), and CD154 (CD40L) are members of the tumor necrosis factor family of costimulatory… 
Highly Cited
1997
Highly Cited
1997
Functional B cell abnormalities in HIV type 1 infection: role of CD40L and CD70.
Early in HIV-1 infection, B cell responses to T cell-dependent antigens are impaired. In addition to the receptor-ligand pair… 
Highly Cited
1995
Highly Cited
1995
Direct cellular communications between CD45R0 and CD45RA T cell subsets via CD27/CD70.
The engagement of CD27 with its ligand CD70 is considered to play an important role in T cell costimulation. In the present study… 
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