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CD70 Antigen

Known as: CD27 Ligand, Ligand, CD27, CD27L Protein 
A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds to CD27 ANTIGEN. It is found on activated T… 
National Institutes of Health

Related topics

Related topics

20 relations
Apoptosis Regulatory ProteinsCD70 geneCell DeathCell Proliferation Regulatory Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Down-regulation of MBD4 contributes to hypomethylation and overexpression of CD70 in CD4+ T cells in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by lymphocytic infiltration and overproduction… 
2013
2013
L08.05 ARGX-110: A NEUTRALIZING, HUMANIZED MONOCLONAL ANTIBODY TO THE HUMAN CD70 ANTIGEN WITH ENHANCED ADCC PROPERTIES
2004
2004
Induction of T-cell antitumor immunity and protection against tumor growth by secretion of soluble human CD70 molecules
One of the strategies to promote an antitumor response is the genetic modification of tumor cells to induce expression of… 
Highly Cited
2002
Highly Cited
2002
CD70/CD27 ligand, a member of the TNF family, is expressed in human brain tumors
CD70 (CD27 ligand) has been implicated in proapoptotic signals mediated by its receptor CD27 in lymphocytes as well as in… 
Highly Cited
1998
Highly Cited
1998
Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells.
CD70 (CD27 ligand (CD27L)), CD153 (CD30L), and CD154 (CD40L) are members of the tumor necrosis factor family of costimulatory… 
Highly Cited
1998
Highly Cited
1998
Generation of plasma cells from peripheral blood memory B cells: synergistic effect of interleukin-10 and CD27/CD70 interaction.
B cells can differentiate into the antibody-secreting cells, plasma cells, whereas the crucial signals that positively control… 
1997
1997
CD70 (CD27 LIGAND) EXPRESSION BY SYNOVIAL FLUID CD4+ T LYMPHOCYTES IN RHEUMATOID ARTHRITIS : COMMENT ON THE ARTICLE BY KOHEM ET AL. AUTHORS' REPLY
Highly Cited
1997
Highly Cited
1997
CD154/CD40 and CD70/CD27 interactions have different and sequential functions in T cell-dependent B cell responses: enhancement of plasma cell differentiation by CD27 signaling.
CD40, a TNF receptor family member, plays a central role in T cell-mediated B cell activation. We have recently demonstrated that… 
Highly Cited
1996
Highly Cited
1996
Phenotype and function of human B cells expressing CD70 (CD27 ligand)
CD70, the cellular ligand of the tumor necrosis factor receptor family member CD27, can be found on a limited number of germinal… 
Highly Cited
1995
Highly Cited
1995
CD27-CD27 ligand/CD70 interactions enhance alloantigen-induced proliferation and cytolytic activity in CD8+ T lymphocytes.
To study the role of CD27-CD27 ligand (CD27L)/CD70 interactions in the generation of murine allospecific T cell responses, SF9… 
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