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CD70 Antigen

Known as: CD27 Ligand, Ligand, CD27, CD27L Protein 
A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds to CD27 ANTIGEN. It is found on activated T… 
National Institutes of Health

Related topics

Related topics

20 relations
Apoptosis Regulatory ProteinsCD70 geneCell DeathCell Proliferation Regulatory Process

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Abstract 2321: Dual-function of CD27-CD70 costimulatory signal in CAR T cell therapy
Purpose: To investigate the function of co-stimulatory molecule CD27 on the antitumor efficacy of chimeric antigen receptor (CAR… 
2013
2013
Abstract 5470: Pre-clinical characterization of ARGX-110: A neutralizing, humanized monoclonal antibody to the human CD70 antigen with enhanced ADCC properties.
The expression of CD70 is normally restricted to activated B- and T- cells, as well as mature dendritic cells. Overexpression has… 
Highly Cited
1998
Highly Cited
1998
Enhancement of antitumor immunity by expression of CD70 (CD27 ligand) or CD154 (CD40 ligand) costimulatory molecules in tumor cells.
CD70 (CD27 ligand (CD27L)), CD153 (CD30L), and CD154 (CD40L) are members of the tumor necrosis factor family of costimulatory… 
1997
1997
CD70 (CD27 LIGAND) EXPRESSION BY SYNOVIAL FLUID CD4+ T LYMPHOCYTES IN RHEUMATOID ARTHRITIS : COMMENT ON THE ARTICLE BY KOHEM ET AL. AUTHORS' REPLY
1997
1997
CD27/CD70 interaction contributes to the activation and the function of human autoreactive CD27+ regulatory T cells.
CD27, a tumor necrosis factor receptor family member, is a constimulatory molecule for T and B cell activation. We demonstrate… 
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