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CD70 wt Allele

Known as: CD27L, CD27LG, CD70 
Human CD70 wild-type allele is located in the vicinity of 19p13 and is approximately 8 kb in length. This allele, which encodes CD70 antigen protein… 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (1)

CD70 gene
Cell DeathCell Proliferation Regulatory ProcessCytokine Receptor BindingCytokine Signaling

Papers overview

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Review
2017
Review
2017
Abstract 4589: Preclinical investigation of SGN-CD70A antibody-drug conjugate in T cell lymphomas
CD70 is a member of the tumor necrosis factor (TNF) superfamily and aberrantly expressed in several solid tumors and a variety of… 
2017
2017
CD70 as a novel target of CAR-T-cell therapy for gliomas.
148Background: Gliomas are the most common primary malignant brain tumor and are uniformly lethal. Cancer immunotherapy has the… 
2015
2015
P5 Retrospective analysis on the expression of CD70 in squamous cell carcinoma of the head and neck (HNSCC) and its relation to patient outcome
2014
2014
AB0126 CD70 Expressing CD4 T Cells Produce IFN-Γ and IL-17 in Rheumatoid Arthritis
Background CD70 expressing CD4 T cells are enriched in rheumatoid arthritis (RA) and promote autoimmunity via costimulatory CD70… 
2011
2011
CD70 and Th17 are involved in human contact sensitivity.
CD70 (CD27L) has been shown to be preferentially expressed on Th1, but not Th2, CD4+ lymphocytes in murine contact sensitivity… 
2010
2010
Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4+ T cell differentiation
Review
2009
Review
2009
Novel antibody-based therapeutic agents targeting CD70: a potential approach for treating Waldenström's macroglobulinemia.
Targeting leukocyte differentiation antigens is a validated approach to develop therapeutic agents for the treatment of cancer… 
2003
2003
The role and expression of CD27 and CD70 lymphocytes in the human tonsil.
In this study, we investigated the expression and function of CD27 and CD70 in the human tonsil. We found that IgG production was… 
1999
1999
Expression of tumour necrosis factor (TNF) receptor/ligand superfamily co‐stimulatory molecules CD40, CD30L, CD27L, and OX40L in murine hearts with chronic ongoing myocarditis caused by Coxsackie…
T‐cell‐mediated myocardial damage has been shown to be involved in acute myocarditis and dilated cardiomyopathy. It is necessary… 
1997
1997
CD40 and IL-4 regulate murine CD27L expression.
It is well known that interactions between accessory molecules on T cells and their ligands on APC play a key role in regulating… 
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