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CD45RO, human

Known as: CD45R0 Antigen, CD45RO Antigen, Receptor-Type Tyrosine-Protein Phosphatase C Isoform CD45RO 
CD45RO is encoded by the human PTPRC gene. This protein is involved in both tyrosine dephosphorylation and lymphocyte activity. It is an isoform of… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (1)

CD45RO Antigens
DephosphorylationEnzyme GeneEsterase GeneHydrolase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Surface activation markers of T lymphocytes: role in the detection of infection in neonates
Diagnosis of perinatal infection in the newborn is difficult; there may be few clinical signs and current tests are slow or non… 
Highly Cited
1995
Highly Cited
1995
Direct cellular communications between CD45R0 and CD45RA T cell subsets via CD27/CD70.
The engagement of CD27 with its ligand CD70 is considered to play an important role in T cell costimulation. In the present study… 
Highly Cited
1994
Highly Cited
1994
Thymic CD45 tyrosine phosphatase regulates apoptosis and MHC-restricted negative selection.
The acquisition of immunologic self-tolerance is governed, in part, by selection mechanisms that occur during intrathymic T cell… 
1994
1994
Expression and ATRA-driven modulation of adhesion molecules in acute promyelocytic leukemia.
On fresh leukemic cells taken from 30 patients with acute promyelocytic leukemia (APL) the membrane expression of a series of… 
Highly Cited
1993
Highly Cited
1993
Gluten Stimulation of Coeliac Mucosa In Vitro Induces Activation (CD25) of Lamina Propria CD4H T cells and Macrophages but no Crypt‐Cell Hyperplasia
Jejunal biopsy specimens from 10 patients with treated coeliac disease and seven non‐coeliac controls were challenged in vitro… 
Highly Cited
1993
Highly Cited
1993
Continuous in vivo activation and transient hyporesponsiveness to TcR/CD3 triggering of human gut lamina propria lymphocytes
Three‐color immunofluorescence and flow cytometric analysis showed that the vast majority of normal human T‐lamina propria… 
1992
1992
Reversal of CD45R isoform switching in CD8+ T cells.
1991
1991
Human CD4+CD45RO+ and CD4+CD45RA+ T cells synergize in response to alloantigens
Alloantigens, unlike recall antigens, activate both CD45RA+ (naive) and CD45RO+ (memory) CD4+ cells to the same extent. These T… 
1991
1991
Detection of hyperreactive T cells in multiple myeloma by multivalent cross-linking of the CD3/TCR complex.
Cellular immunity was investigated in 43 patients with multiple myeloma (MM) by assessing 3HTdR uptake induced by monocyte… 
Highly Cited
1990
Highly Cited
1990
Human CD8+ intraepithelial T lymphocytes are mainly CD45RA−RB+ and show increased co‐expression of CD45R0 in celiac disease
Expression of various CD45 isoforms (RA, RB and R0) on CD3+, CD4+ and CD8+ intraepithelial and lamina propria T cells was… 
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