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CD38 Antigen

Known as: CD38 Ag, Cyclase T10, ADPR, CD38 molecule 
A bifunctional enzyme that catalyzes the synthesis and HYDROLYSIS of CYCLIC ADP-RIBOSE (cADPR) from NAD+ to ADP-RIBOSE. It is a cell surface molecule… 
National Institutes of Health

Related topics

Related topics

15 relations
ADP-Ribosyl Cyclase 1CD38 Ag:PrThr:Pt:Tiss:Ord:Immune stainCD38 geneIn Blood

Broader (3)

CD AntigensDifferentiation AntigensN-Glycosyl Hydrolases

Narrower (1)

Cd38 protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Relationship between the frequency of HIV-specific CD8+ T cells and the level of CD38+CD8+ T cells in untreated HIV-infected individuals.
CD8+ T cells are critical for effective host defenses against viral infections. Studies addressing HIV-induced immune responses… 
Highly Cited
2000
Highly Cited
2000
Localization of the Cyclic ADP-ribose-dependent Calcium Signaling Pathway in Hepatocyte Nucleus*
CD38 is a type II transmembrane glycoprotein found on both hematopoietic and non-hematopoietic cells. It is known for its… 
Highly Cited
1997
Highly Cited
1997
A critical role of Lyn and Fyn for B cell responses to CD38 ligation and interleukin 5.
CD38 ligation on mouse B cells by CS/2, an anti-mouse CD38 mAb, induced proliferation, interleukin 5 (IL-5) receptor alpha chain… 
Highly Cited
1996
Highly Cited
1996
Elevated relative fluorescence intensity of CD38 antigen expression on CD8+ T cells is a marker of poor prognosis in HIV infection: results of 6 years of follow-up.
Relative fluorescence intensity measurements from a flow cytometer were used to evaluate expression of CD38 and HLA-DR antigens… 
Highly Cited
1996
Highly Cited
1996
Coordinated regulation in human T cells of nucleotide-hydrolyzing ecto-enzymatic activities, including CD38 and PC-1. Possible role in the recycling of nicotinamide adenine dinucleotide metabolites.
The human leukocyte surface Ag CD38 was recently identified as a nicotinamide adenine dinucleotide (NAD)(+)-glycohydrolase ecto… 
Highly Cited
1995
Highly Cited
1995
CD38 ligation induces tyrosine phosphorylation of Bruton tyrosine kinase and enhanced expression of interleukin 5-receptor alpha chain: synergistic effects with interleukin 5.
Mouse CD38 has been implicated in the regulation of both B-cell proliferation and protection of B cells from irradiation-induced… 
Highly Cited
1994
Highly Cited
1994
Interaction between endothelium and CD4+CD45RA+ lymphocytes. Role of the human CD38 molecule.
CD38 is a type II transmembrane glycoprotein, which is widely used as a marker for immature and activated lymphocytes, as well as… 
Highly Cited
1993
Highly Cited
1993
A B lymphocyte surface molecule mediating activation and protection from apoptosis via calcium channels.
A rat mAb (NIM-R5) was prepared against a 42-kD B cell activation Ag (p42). The expression of p42 is increased upon activation… 
Highly Cited
1993
Highly Cited
1993
Rapid induction of CD38 antigen on myeloid leukemia cells by all trans-retinoic acid.
The CD38 or T10 molecule is one of the least understood differentiation antigens. Virtually no information is available on the… 
Highly Cited
1992
Highly Cited
1992
Identification and characterization of the murine homologue of CD22, a B lymphocyte-restricted adhesion molecule.
The human B lymphocyte-specific Ag, CD22, is a cell adhesion molecule expressed on the surface during a narrow window of B cell… 
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