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CD33 antigen

Known as: CD33, gp67, Glycoprotein, Sialic Acid Binding Ig like Lectin 3 
A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec… 
National Institutes of Health

Related topics

Related topics

14 relations

Broader (1)

CD Antigens
CD33 Ag:PrThr:Pt:Tiss:Ord:Immune stainCD33 Expressing Cell CountCD33 geneCD33 wt Allele

Narrower (1)

CD33 protein, human

Papers overview

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Highly Cited
2017
Highly Cited
2017
Novel Therapeutic Approach to Improve Hematopoiesis in low risk MDS by Targeting MDSCs with The Fc-engineered CD33 Antibody BI 836858
We recently reported that the accumulation of myeloid-derived suppressor cells (MDSC), defined as CD33+HLA-DR−Lin−, has a direct… 
Highly Cited
2015
Highly Cited
2015
Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex
Highly Cited
2014
Highly Cited
2014
Rapid evolution of binding specificities and expression patterns of inhibitory CD33‐related Siglecs in primates
Siglecs are sialic acid‐binding Ig‐like lectins that recognize sialoglycans via amino‐terminal V‐set domains. CD33‐related… 
Highly Cited
2013
Highly Cited
2013
Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta
Highly Cited
2010
Highly Cited
2010
Effective Elimination of Acute Myeloid Leukemic Cells by Recombinant Bispecific Antibody Derivatives Directed Against CD33 and CD16
Single-chain Fv triplebodies (sctb), consisting of a single polypeptide chain with 3 single-chain antibody variable fragments… 
Highly Cited
2007
Highly Cited
2007
Expression of the target receptor CD33 in CD34+/CD38−/CD123+ AML stem cells
Background  CD33 (Siglec‐3) is becoming increasingly important as a target of antibody‐mediated therapy in acute myeloid… 
Highly Cited
2007
Highly Cited
2007
CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover.
CD33 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family of inhibitory receptors and a therapeutic… 
Highly Cited
2001
Highly Cited
2001
Cloning and Characterization of a Novel Mouse Siglec, mSiglec-F
A novel mouse Siglec (mSiglec-F) belonging to the subfamily of Siglec-3-related Siglecs has been cloned and characterized. Unlike… 
Highly Cited
1999
Highly Cited
1999
The Myeloid-specific Sialic Acid-binding Receptor, CD33, Associates with the Protein-tyrosine Phosphatases, SHP-1 and SHP-2*
The myeloid restricted membrane glycoprotein, CD33, is a member of the recently characterized “sialic acid-binding immunoglobulin… 
Highly Cited
1995
Highly Cited
1995
Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.
CD33 is a member of the Ig superfamily that is restricted to cells of the myelomonocytic lineage but whose functions and binding… 
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