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CD226 wt Allele

Known as: CD226 Molecule wt Allele, DNAM-1, CD226 Antigen Gene 
Human CD226 wild-type allele is located in the vicinity of 18q22.3 and is approximately 96 kb in length. This allele, which encodes CD226 antigen… Expand
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Specific NK cell killer inhibitory receptor (KIR):HLA haplotype combinations have been associated with successful clearance of… Expand
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Highly Cited
2010
Highly Cited
2010
A role for NK cells in therapeutic intervention for hematologic malignancies, such as acute myeloid leukemia and multiple myeloma… Expand
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Highly Cited
2009
Highly Cited
2009
There is much evidence to support a role for natural killer (NK) cells in controlling the progression of multiple myeloma (MM), a… Expand
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Highly Cited
2008
Highly Cited
2008
Since the identification of ligands for human and mouse DNAM-1, emerging evidence has suggested that DNAM-1 plays an important… Expand
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Highly Cited
2008
Highly Cited
2008
INTRODUCTION Ewing sarcoma (EWS) is a malignant bone-associated sarcoma, with poor prognosis in case of metastasis or relapse. To… Expand
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Highly Cited
2006
Highly Cited
2006
In this study, we demonstrate the involvement of DNAM-1-triggering receptor and its ligands, poliovirus receptor (PVR) and Nectin… Expand
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Highly Cited
2004
Highly Cited
2004
CD226 (DNAM-1) is an adhesion molecule involved in NK and T cell-mediated cytotoxicity against certain tumors. Here, we have… Expand
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Highly Cited
2004
Highly Cited
2004
In the present study, we assessed the susceptibility of freshly isolated neuroblastoma cells to killing mediated by normal human… Expand
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Highly Cited
2003
Highly Cited
2003
Upon antigen recognition by the T cell receptor, lymphocyte function–associated antigen 1 (LFA-1) physically associates with the… Expand
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Highly Cited
1999
Highly Cited
1999
Whereas ligation of the DNAM-1 adhesion molecule triggers cytotoxicity mediated by normal NK and T cells, this function was… Expand
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