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CD1C protein, human

Known as: CD1c Antigen, BDCA-1, Cortical Thymocyte Antigen CD1C 
T-cell surface glycoprotein CD1c (333 aa, ~38 kDa) is encoded by the human CD1C gene. This protein is involved in lipid and glycolipid antigen… 
National Institutes of Health

Related topics

Related topics

13 relations
Antigen PresentationCD1C geneCD1C wt AlleleImmune System Processes

Broader (2)

Antigens, CD1Glycoproteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
HIV-1 Selectively Infects a Subset of Nonmaturing BDCA1-Positive Dendritic Cells in Human Blood1
The infection of cultured monocyte-derived dendritic cells (DCs) with HIV-1 involves CD4 and CCR5 receptors, while transmission… 
Highly Cited
2004
Highly Cited
2004
Metastatic melanoma secreted IL-10 down-regulates CD1 molecules on dendritic cells in metastatic tumor lesions.
Highly Cited
2002
Highly Cited
2002
CD1-mediated γ/δ T Cell Maturation of Dendritic Cells
Immature myeloid dendritic cells (DCs) express only low levels of major histocompatibility complex (MHC) class II but express… 
Highly Cited
2002
Highly Cited
2002
Expression profiling of B cell chronic lymphocytic leukemia suggests deficient CD1-mediated immunity, polarized cytokine response, altered adhesion and increased intracellular protein transport and…
We used oligonucleotide microarrays to profile the expression of chronic lymphocytic leukemia (CLL) B cells from eight patients… 
Review
2001
Review
2001
CD1-specific T cells in microbial immunity.
Highly Cited
2000
Highly Cited
2000
Human Double-Negative T Cells in Systemic Lupus Erythematosus Provide Help for IgG and Are Restricted by CD1c1
To understand the mechanism of T cell help for IgG production in systemic lupus erythematosus (SLE) we investigated the response… 
Highly Cited
2000
Highly Cited
2000
Intersection of Group I CD1 Molecules and Mycobacteria in Different Intracellular Compartments of Dendritic Cells1
Human CD1a, CD1b, and CD1c molecules can present mycobacterial glycolipids to T cells. Because phagosomes containing viable… 
Highly Cited
2000
Highly Cited
2000
Self-Recognition of Cd1 by γ/δ T Cells
The specificity of immunoglobulins and α/β T cell receptors (TCRs) provides a framework for the molecular basis of antigen… 
Highly Cited
1998
Highly Cited
1998
Neutrophil Granulocyte–committed Cells Can Be Driven to Acquire Dendritic Cell Characteristics
Polymorphonuclear granulocytes (PMNs) are thought to fulfill their role in host defense primarily via phagocytosis and release of… 
Highly Cited
1990
Highly Cited
1990
Human epidermal Langerhans cells undergo profound morphologic and phenotypical changes during in vitro culture.
Morphology, phenotype, and enzyme activity of highly enriched (80%) unlabeled human epidermal Langerhans cells (LC) have been… 
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