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CC 1065

Known as: Benzo(1,2-b:4,3-b')dipyrrole-3(2H)-carboxamide, 7-((1,6-dihydro-4-hydroxy-5-methoxy-7-((4,5,8,8a-tetrahydro-7-methyl-4-oxocyclopropa(c)pyrrolo(3,2-e)indol-2(1H)-yl)carbonyl)benzo(1,2-b:4,3-b')dipyrrol-3(2H)-yl)carbonyl)-1,6-dihydro-4-hydroxy-5-methoxy-, CC-1065 
National Institutes of Health

Papers overview

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Review
2009
Review
2009
to define subtle relationships between structure, reactivity, reaction regioselectivity and biological potency 
Review
1999
Review
1999
Review
1996
Review
1996
Review
1995
Review
1995
Key studies defining the DNA alkylation properties and selectivity of a new class of exceptionally potent, naturally occurring… 
Highly Cited
1988
Highly Cited
1988
CC-1065 is a potent antitumor antibiotic that binds covalently to N3 of adenine in the minor groove of DNA. The CC-1065 molecule… 
Highly Cited
1985
Highly Cited
1985
CC-1065 is a unique antitumor antibiotic produced by Streptomyces zelensis. The potent cytotoxic effects of this drug are thought… 
Highly Cited
1984
Highly Cited
1984
Sequence-dependent variations in DNA revealed by x-ray crystallographic studies have suggested that certain DNA-reactive drugs… 
Highly Cited
1984
Highly Cited
1984
It was previously shown that the potent new DNA-binding antibiotic, CC-1065, prolonged life span, but was not curative, when… 
Highly Cited
1982
Highly Cited
1982
CC-1065 (NSC 298223), a potent new antitumor antibiotic produced by Streptomyces zelensis, interacts strongly with double… 
Highly Cited
1978
Highly Cited
1978
A new antitumor antibiotic is produced in fermentation liquors of Streptomyces zelensis sp.n. The antibiotic is biologically…