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CC 1065

Known as: Benzo(1,2-b:4,3-b')dipyrrole-3(2H)-carboxamide, 7-((1,6-dihydro-4-hydroxy-5-methoxy-7-((4,5,8,8a-tetrahydro-7-methyl-4-oxocyclopropa(c)pyrrolo(3,2-e)indol-2(1H)-yl)carbonyl)benzo(1,2-b:4,3-b')dipyrrol-3(2H)-yl)carbonyl)-1,6-dihydro-4-hydroxy-5-methoxy-, CC-1065 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (2)

Antibiotics, AntineoplasticIndoles
NSC 298223

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
New cc-1065 analogs and their conjugates
FIELD: pharmacology. SUBSTANCE: invention relates to a compound of formula or a pharmaceutically acceptable salt thereof, wherein… 
2009
2009
New cc-1065 analogs and its complex
The present invention relates to novel analogs and their complexes of DNA alkylating agents CC-1065. The invention further… 
1996
1996
3-methyladenine-DNA-glycosylase and O6-alkyl guanine-DNA-alkyltransferase activities and sensitivity to alkylating agents in human cancer cell lines.
The activities and the expression of 3-methyladenine glycosylase (3-meAde gly) and O6-alkylguanine-DNA-alkyltransferase (O6 ATase… 
1991
1991
신규한 cc-1065 유사체
본 발명은 화학적 중간체로서 유용한 하기 일반식(I) 및 (II)의 몇몇 합성적으로 수득한 신규 화합물들을 제공한다 : 대표적인 일반식(I) 또는 (II… 
1991
1991
Novel cc-1065 analogues
The present invention provides novel compounds which ever obtained in the synthesis of some useful to the general formula (I) and… 
1987
1987
Theoretical study of the sequence specificity in the covalent binding of the antitumor drug CC-1065 to DNA.
A theoretical modelling is presented of the covalent adducts of the antitumor agent CC-1065 with B-DNA. The optimal complexes are… 
1986
1986
Depletion of nicotinamide adenine dinucleotide in normal and xeroderma pigmentosum fibroblast cells by the antitumor drug CC-1065.
CC-1065 is an extremely potent antitumor antibiotic that forms a well-defined adduct with DNA in which the molecule lies within… 
1985
1985
CC-1065 transformations.
This report defines the transformations that antitumor antibiotic CC-1065 underwent under basic and acidic conditions. The… 
1982
1982
[Identification of the antibiotic formed by a Str. canulus 106/78 culture with antibiotic CC-1065].
: An antibiotic with a melting point of at least 340 degrees C, [alpha]D + 100 degrees (c 1 per cent in dimethylformamide) was… 
1978
1978
Isolation, characterization, and preliminary antitumor evaluation of cc-1065, a potent new agent from fermentation. Abstr.
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