CBR1 protein, human

Known as: carbonyl reductase 1, human, Prostaglandin-E(2) 9-Reductase, 15-Hydroxyprostaglandin Dehydrogenase 
Carbonyl reductase [NADPH] 1 (277 aa, ~30 kDa) is encoded by the human CBR1 gene. This protein plays a role in the reduction of carbonyl compounds.

Topic mentions per year

Topic mentions per year

1995-2016
012319952016

Papers overview

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2015
2015
The anthracyclines doxorubicin and daunorubicin are used in the treatment of various human and canine cancers, but anthracycline… (More)
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2015
2015
Doxorubicin (DOX) is widely used for the treatment of a wide range of cancers such as breast and lung cancers, and malignant… (More)
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2014
2014
A novel carbonyl reductase (AcCR) catalyzing the asymmetric reduction of ketones to enantiopure alcohols with anti-Prelog… (More)
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2012
2012
MicroRNAs (miRNAs) are small RNAs responsible for the post-transcriptional regulation of a variety of human genes. To date, their… (More)
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2012
2012
BACKGROUND The present study investigated tumor proliferation in a tumor model using murine ovarian cancer cells with increased… (More)
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2008
2008
Carbonyl reductase 1 (CBR1) reduces the anticancer anthracyclines doxorubicin and daunorubicin into the cardiotoxic metabolites… (More)
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2008
2008
The molecular mechanisms of growth suppression by retinoic acid (RA) were examined. Our results suggest that the cytostatic… (More)
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2004
2004
A growing body of evidence suggests that oxidative stress is a common underlying mechanism in the pathogenesis of… (More)
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2003
2003
A NADPH-dependent carbonyl reductase (CSCR1) was puriˆed to homogeneity from Cylindrocarpon sclerotigenum IFO 31855. The enzyme… (More)
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1998
1998
3a-Hydroxysteroid dehydrogenase/carbonyl reductase (3a-HSD/CR) from Comamonas testosteroni, a bacterium that is able to grow on… (More)
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