CBR1 gene

Known as: Carbonyl Reductase 1 Gene, CBR1, SDR21C1 
This gene plays a role in the metabolism of a wide variety of carbonyl compounds.
National Institutes of Health

Papers overview

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2010
2010
UNLABELLED Human carbonyl reductase 1 (CBR1) converts the antitumor drug and anthracycline daunorubicin (DNR) into the alcohol… (More)
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2008
2008
The present study aimed to identify polymorphic genes encoding carbonyl reductases (CBR1, CBR3) and investigate their influence… (More)
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2007
2007
Human carbonyl reductase 1 (CBR1) metabolizes a variety of substrates, including the anticancer doxorubicin and the antipsychotic… (More)
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2007
2007
Anthracycline antibiotics (e.g. doxorubicin and daunorubicin) are among the most effective and widely used anticancer drugs… (More)
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Highly Cited
2005
Highly Cited
2005
We have implemented an unbiased cell morphology-based screen to identify small-molecule modulators of cellular processes using… (More)
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2002
2002
BACKGROUND & AIMS Transient lower esophageal sphincter relaxations (TLESRs) are the major cause of gastroesophageal acid reflux… (More)
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2001
2001
We have recently reported a novel function for carbonyl reductase (CR), namely, its ability to modulate the metastatic potential… (More)
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2001
2001
Porcine testicular carbonyl reductase (PTCR) belongs to the short chain dehydrogenases/reductases (SDR) superfamily and catalyzes… (More)
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1997
1997
We have determined the crystal structures of complexes of phosphoinositide-specific phospholipase C-delta1 from rat with calcium… (More)
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1994
1994
Arachidonoyl ethanolamide (anandamide) is a naturally occurring brain constituent that binds to a specific brain cannabinoid… (More)
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