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CALR gene

Known as: Sicca syndrome antigen A (autoantigen Ro; calreticulin), SSA, CALR 
This gene plays a role in calcium binding and protein folding.
National Institutes of Health

Related topics

Related topics

14 relations
ApoptosisCALR Gene MutationCalcium BindingCell Cycle Control

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CALR wt Allele

Papers overview

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Highly Cited
2003
Highly Cited
2003
Calreticulin Is at the Surface of Circulating Neutrophils and Uses CD59 as an Adaptor Molecule*
Calreticulin, which has been proposed to be a C1q receptor on neutrophils, has neither a transmembrane domain nor a GPI-anchor… 
Highly Cited
2001
Highly Cited
2001
Transient dissociation of polyribosomes and concurrent recruitment of calreticulin and calmodulin transcripts in gravistimulated maize pulvini.
The dynamics of polyribosome abundance were studied in gravistimulated maize (Zea mays) stem pulvini. During the initial 15 min… 
Highly Cited
1998
Highly Cited
1998
Multiple Molecular Chaperones Interact with Apolipoprotein B during Its Maturation
The present study was undertaken to identify and characterize molecular chaperones that assist in the folding of apolipoprotein… 
Highly Cited
1993
Highly Cited
1993
The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes
Cytolytic T lymphocytes (CTL), natural killer cells, and lymphokine- activated killer (LAK) cells are cytolytic cells known to… 
Highly Cited
1993
Highly Cited
1993
Subcellular distribution of Ro ribonucleoprotein complexes and their constituents.
Ro ribonucleoprotein particles (Ro RNPs) are complexes of several proteins with a small RNA polymerase III-transcribed Ro RNA… 
Highly Cited
1991
Highly Cited
1991
Characterization of the autoantigen calreticulin.
Anti-Ro/SS-A antibodies are commonly found in the sera of patients with Sjögren's syndrome and SLE. These antibodies also occur… 
Highly Cited
1986
Highly Cited
1986
Cryoglobulinemia in autoimmune rheumatic diseases. Evidence of circulating monoclonal cryoglobulins in patients with primary Sjögren's syndrome.
The incidence and nature of cryoglobulins, as well as their correlation with the clinical and serologic picture of Sjögren's… 
Highly Cited
1986
Highly Cited
1986
Association of La and Ro antigens with intracellular structures in HEp-2 carcinoma cells.
Monoclonal antibodies were raised against homogeneous Ro and La antigens, two proteins associated with Ro and La… 
Highly Cited
1985
Highly Cited
1985
Ro (SS-A) antibody and antigen in a patient with congenital complete heart block.
Congenital complete heart block is closely associated with the presence of anti-Ro (SS-A) autoantibodies. Quantitative solid… 
Highly Cited
1982
Highly Cited
1982
Suppression of natural killing in vitro by monocytes and polymorphonuclear leukocytes: requirement for reactive metabolites of oxygen.
Natural killer cells spontaneously lyse certain tumor cells and may defend against malignancy. We have previously shown that… 
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