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CALR gene

Known as: Sicca syndrome antigen A (autoantigen Ro; calreticulin), SSA, CALR 
This gene plays a role in calcium binding and protein folding.
National Institutes of Health

Related topics

Related topics

14 relations
ApoptosisCALR Gene MutationCalcium BindingCell Cycle Control

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CALR wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2001
Highly Cited
2001
An Interaction between Ricin and Calreticulin That May Have Implications for Toxin Trafficking*
Here we demonstrate that ricin is able to interact with the molecular chaperone calreticulin both in vitro and in vivo. The… 
Highly Cited
1998
Highly Cited
1998
Multiple Molecular Chaperones Interact with Apolipoprotein B during Its Maturation
The present study was undertaken to identify and characterize molecular chaperones that assist in the folding of apolipoprotein… 
Highly Cited
1998
Highly Cited
1998
Evidence that C1q binds specifically to CH2-like immunoglobulin gamma motifs present in the autoantigen calreticulin and interferes with complement activation.
Calreticulin (CRT) is located predominantly in the endoplasmic reticulum (ER) of cells, where it functions as a quality control… 
Highly Cited
1996
Highly Cited
1996
The Related Molecular Chaperones Calnexin and Calreticulin Differentially Associate with Nascent T Cell Antigen Receptor Proteins within the Endoplasmic Reticulum*
Assembly of the multisubunit T cell antigen receptor (TCR) complex is an intricate process requiring coordinated regulation of at… 
Highly Cited
1996
Highly Cited
1996
Inhibition of Retinoic Acid Receptor Function and Retinoic Acid-regulated Gene Expression in Mouse Melanoma Cells by Calreticulin
Calcium is a second messenger that controls a wide variety of cellular functions. Because of its multiple actions, there is a… 
Highly Cited
1996
Highly Cited
1996
Isolation of a full-length cDNA encoding calreticulin from a PCR library of in vitro zygotes of maize
A full-size cDNA clone (1614 bp) encoding calreticulin was isolated from a PCR-based cDNA library of maize in vitro zygotes… 
Highly Cited
1995
Highly Cited
1995
Calreticulin inhibits vitamin D3 signal transduction.
Calreticulin is a calcium binding protein present primarily in the lumen of the endoplasmic reticulum. However, it can also… 
Highly Cited
1994
Highly Cited
1994
Cytotoxic effects of antibodies to proteinase 3 (C‐ANCA) on human endothelial cells
Autoantibodies directed against cytoplasmic antigens of neutrophils (ANCA), especially those with specificity for proteinase 3… 
Highly Cited
1991
Highly Cited
1991
Identification and immunolocalization of calreticulin in pancreatic cells: no evidence for "calciosomes".
Highly Cited
1987
Highly Cited
1987
Implications of anti-Ro/Sjögren's syndrome A antigen autoantibody in normal sera for autoimmunity.
We have applied a sensitive assay to analyze lupus and Sjögren's syndrome autoantibodies in 40 normal sera. Seven of these bound… 
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