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C1GALT1C1 gene

Known as: C1GALT1C1, CORE 1 BETA-3-GALACTOSYLTRANSFERASE-SPECIFIC MOLECULAR CHAPERONE, C1GALT2 
This gene plays a role as a chaperone in generation of the common core 1 O-glycan structure.
National Institutes of Health

Related topics

Related topics

4 relations
C1GALT1 genecellular response to unfolded proteinintracellular protein transportprotein folding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Overexpression of Cosmc suppresses cell migration and invasion in different subtypes of breast cancer cells via Tn and T glycans
Abstract Objectives: The high mortality of breast cancer (BC) is associated with the strong metastatic properties of primary… 
2016
2016
Potential diagnostic biomarkers for IgA nephropathy: a comparative study pre- and post-tonsillectomy
ObjectiveThe proteins BAFF, ST6GALNAC2, C1GALT1, and COSMC in peripheral blood mononuclear cells (PBMCs) and plasma levels of… 
2016
2016
The cytokine-cosmc signaling axis upregulates the tumor-associated carbohydrate antigen Tn
Tn antigen (GalNAc-α-O-Ser/Thr), a mucin-type O-linked glycan, is a well-established cell surface marker for tumors and its… 
2015
2015
Aberrant Cosmc genes result in Tn antigen expression in human colorectal carcinoma cell line HT-29.
The Tn antigen, which arises from mutation in the Cosmc gene is one of the most common tumor associated carbohydrate antigens… 
2015
2015
COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer
Human pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal malignancies in the world and despite… 
2014
2014
Accelerating Genome Editing in CHO Cells Using CRISPR Cas9 and CRISPy, a Web-Based Target Finding Tool
Chinese hamster ovary (CHO) cells are widely used in the biopharmaceutical industry as a host for the production of complex… 
2013
2013
Activation of the Interleukin-4/Signal Transducer and Activator of Transcription 6 Signaling Pathway and Homeodomain-Interacting Protein Kinase 2 Production by Tonsillar Mononuclear Cells in IgA…
Background/Aim: Clinical development and exacerbation of IgA nephropathy (IgAN) are frequently preceded by episodes of upper… 
2010
2010
The role of C1GALT1C1 in lipopolysaccharide-induced IgA1 aberrant O-glycosylation in IgA nephropathy.
PURPOSE IgA1 aberrant O-glycosylation is one of the main pathogenetic features of IgA nephropathy (IgAN). This study attempted to… 
2008
2008
Immunocytochemical analysis for intracellular dynamics of C1GalT associated with molecular chaperone, Cosmc.
Review
2007
Review
2007
Mutant mice provide new insight into the role of (mis-)glycation in IgA nephropathy and other glomerular diseases.
Keywords: aminopeptidase N; glomerular;glomerulonephritis; glycosylation; IgA; podocalyxinIn the 24 October 2006 issue of PNAS… 
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