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C1GALT1 gene

Known as: C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, T SYNTHASE 
This gene is involved in generation of the common core 1 O-glycan structure.
National Institutes of Health

Related topics

Related topics

3 relations
C1GALT1 protein, humanC1GALT1C1 geneglycosylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Loss of the Golgi Matrix Protein 130 Cause Aberrant IgA1 Glycosylation in IgA Nephropathy
Background: Aberrant O-glycosylation IgA1 production is a major factor in the pathogenesis of IgA nephropathy, but the underlying… 
2016
2016
Potential diagnostic biomarkers for IgA nephropathy: a comparative study pre- and post-tonsillectomy
ObjectiveThe proteins BAFF, ST6GALNAC2, C1GALT1, and COSMC in peripheral blood mononuclear cells (PBMCs) and plasma levels of… 
Review
2015
Review
2015
The Genetics of IgA Nephropathy: An Overview from Western Countries
Background: IgA nephropathy (IgAN) is the commonest primary glomerulonephritis worldwide and a significant cause of chronic… 
2014
2014
Capsaicin induces high expression of BAFF and aberrantly glycosylated IgA1 of tonsillar mononuclear cells in IgA nephropathy patients.
2013
2013
Activation of the Interleukin-4/Signal Transducer and Activator of Transcription 6 Signaling Pathway and Homeodomain-Interacting Protein Kinase 2 Production by Tonsillar Mononuclear Cells in IgA…
Background/Aim: Clinical development and exacerbation of IgA nephropathy (IgAN) are frequently preceded by episodes of upper… 
2012
2012
Targeted Disruption of Core 1 β1,3-galactosyltransferase (C1galt1) Induces Apical Endocytic Trafficking in Human Corneal Keratinocytes
Background Exposed mucosal surfaces limit constitutive endocytosis under physiological conditions to prevent uptake of… 
2012
2012
Abnormal miR-148 b Expression Promotes Aberrant Glycosylation of IgA 1 in IgA Nephropathy
Aberrant O-glycosylation in the hinge region of IgA1 characterizes IgA nephropathy. The mechanisms underlying this abnormal… 
2010
2010
Quercetin supplementation and its effect on human monocyte gene expression profiles in vivo
Quercetin has been described as having a wide range of beneficial effects in humans, ranging from anti-carcinogenic properties to… 
2008
2008
Immunocytochemical analysis for intracellular dynamics of C1GalT associated with molecular chaperone, Cosmc.
2008
2008
No evidence for a role of cosmc-chaperone mutations in European IgA nephropathy patients.
BACKGROUND Altered IgA1 galactosylation is involved in the pathogenesis of IgA nephropathy (IgAN). The galactosyltransferase core… 
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