C1GALT1 gene

Known as: C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, T SYNTHASE 
This gene is involved in generation of the common core 1 O-glycan structure.

Topic mentions per year

Topic mentions per year

2002-2018
051020022018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Altered glycosylation is a hallmark of cancer. The core 1 β1,3-galactosyltransferase (C1GALT1) controls the formation of mucin… (More)
Is this relevant?
2012
2012
Cosmc is the specific molecular chaperone in the endoplasmic reticulum for T-synthase, a Golgi β3-galactosyltransferase that… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2012
2012
To identify roles in spermatogenesis for major subclasses of N- and O-glycans and Notch signaling, male mice carrying floxed… (More)
Is this relevant?
2008
2008
Regulatory pathways for protein glycosylation are poorly understood, but expression of branchpoint enzymes is critical. A key… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2007
2007
IgA nephropathy (IgAN) is a polygenic disorder and the precise role of genetic factors remains elusive. Increasing evidences have… (More)
Is this relevant?
2006
2006
The common O-glycan core structure in animal glycoproteins is the core 1 disaccharide Galbeta1-3GalNAcalpha1-Ser/Thr, which is… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Tn syndrome is a rare autoimmune disease in which subpopulations of blood cells in all lineages carry an incompletely… (More)
Is this relevant?
2004
2004
The core 1 beta1-3-galactosyltransferase (T-synthase) transfers Gal from UDP-Gal to GalNAcalpha1-Ser/Thr (Tn antigen) to form the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Human core 1 beta3-galactosyltransferase (C1beta3Gal-T) generates the core 1 O-glycan Galbeta1-3GalNAcalpha1-SerThr (T antigen… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2002
2002
The common core 1 O-glycan structure Galbeta1--> 3GalNAc-R is the precursor for many extended mucin-type O-glycan structures in… (More)
Is this relevant?