C-terminal type I collagen telopeptide

Known as: MMP-Generated C-Terminal Telopeptide Type 1 Collagen, CTX-MMP, Cross-Linked C-Terminal Telopeptide of Type I Collagen Generated by Matrix Metalloproteinases 
This polypeptide is comprised of the carboxy-terminal portions of fibrillar collagen, which are joined through trivalent crosslinks and released… (More)
National Institutes of Health

Related topics

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15 relations
C-telopeptideCell AdhesionCell MovementCollagen Gene
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Broader (1)

collagen type I trimeric cross-linked peptide

Papers overview

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Highly Cited
2007
Highly Cited
2007
REGIONAL CLIMATE MODELING FOR THE DEVELOPING WORLD The ICTP RegCM
SEPTEMBER 2007 AMERICAN METEOROLOGICAL SOCIETY | REGIONAL CLIMATE MODELING FOR THE DEVELOPING WORLD The ICTP RegCM3 and RegCNET… (More)
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Highly Cited
2003
Highly Cited
2003
The type I collagen fragments ICTP and CTX reveal distinct enzymatic pathways of bone collagen degradation.
Bone resorption may generate collagen fragments such as ICTP and CTX, which can be quantified in serum and/or urine by using… (More)
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Highly Cited
2003
Highly Cited
2003
Myocardial collagen turnover in hypertrophic cardiomyopathy.
BACKGROUND Myocardial interstitial fibrosis is a characteristic of hypertrophic cardiomyopathy (HCM). This study evaluates the… (More)
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Highly Cited
2001
Highly Cited
2001
Training-induced changes in peritendinous type I collagen turnover determined by microdialysis in humans.
1. Acute exercise is found to increase collagen type I formation locally in peritendinous connective tissue of the Achilles… (More)
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Highly Cited
2000
Highly Cited
2000
Immunochemical characterization of assay for carboxyterminal telopeptide of human type I collagen: loss of antigenicity by treatment with cathepsin K.
The assay for the cross-linked carboxyterminal telopeptide of type I collagen (ICTP) has been shown to reflect increased type I… (More)
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Highly Cited
1999
Highly Cited
1999
Type I collagen synthesis and degradation in peritendinous tissue after exercise determined by microdialysis in humans.
1. Physical activity is known to increase type I collagen synthesis measured as the concentration of biomarkers in plasma. By the… (More)
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Highly Cited
1997
Highly Cited
1997
A matrix metalloproteinase inhibitor reduces bone-type collagen degradation fragments and specific collagenases in gingival crevicular fluid during adult periodontitis
Objective and Design: To determine whether an inhibitor of matrix metalloproteinases (MMPs), administered to human subjects in a… (More)
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Highly Cited
1993
Highly Cited
1993
Radioimmunoassay for the pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen: a new serum marker of bone collagen degradation.
We developed a radioimmunoassay (RIA) for the carboxy-terminal telopeptides of type I collagen (ICTP), cross-linked with the… (More)
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Highly Cited
1993
Highly Cited
1993
Serum markers of type I collagen formation and degradation in metabolic bone disease: correlation with bone histomorphometry.
Type I collagen makes up more than 90% of bone matrix. Therefore, analysis of antigens related to collagen formation and… (More)
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1992
1992
Serum concentration of the cross-linked carboxyterminal telopeptide of type I collagen (ICTP) is a useful prognostic indicator in multiple myeloma.
Type I collagen is the main collagen type found in mineralised bone. Specific immunoassays for PICP (carboxyterminal propeptide… (More)
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