• Publications
  • Influence
Global burden of Shigella infections: implications for vaccine development and implementation of control strategies.
TLDR
Shigellosis, which continues to have an important global impact, cannot be adequately controlled with the existing prevention and treatment measures, and innovative strategies, including development of vaccines against the most common serotypes, could provide substantial benefits. Expand
The global burden of cholera.
TLDR
The global burden of cholera, as determined through a systematic review with clearly stated assumptions, is high and provides a contemporary basis for planning public health interventions to control the disease. Expand
Evidence for several waves of global transmission in the seventh cholera pandemic
TLDR
It is shown here that the seventh pandemic has spread from the Bay of Bengal in at least three independent but overlapping waves with a common ancestor in the 1950s, and several transcontinental transmission events are identified. Expand
A Multicentre Study of Shigella Diarrhoea in Six Asian Countries: Disease Burden, Clinical Manifestations, and Microbiology
TLDR
Shigella appears to be more ubiquitous in Asian impoverished populations than previously thought, and antibiotic-resistant strains of different species and serotypes have emerged. Expand
A study of typhoid fever in five Asian countries: disease burden and implications for controls.
TLDR
The incidence of typhoid varied substantially between sites, being high in India and Pakistan, intermediate in Indonesia, and low in China and Viet Nam, and underscore the importance of evidence on disease burden in making policy decisions about interventions to control this disease. Expand
The protective efficacy of polyvalent pneumococcal polysaccharide vaccine.
TLDR
Polyvalent pneumococcal vaccine is efficacious in preventing invasive pneumitiscal infections in immunocompetent patients with indications for its administration and should be used more widely. Expand
Field trial of oral cholera vaccines in Bangladesh: results from three-year follow-up
TLDR
Protection was similar against severe and non-severe cholera, but was significantly lower in children who were vaccinated at 2-5 years than in older persons (63% for BS-WC; 68% for WC); and PE was substantially higher against classical cholero than against El Tor cholERA. Expand
Typhoid fever in children aged less than 5 years
TLDR
The findings challenge the common view that typhoid fever is a disorder of school-age children and of adults, and the optimum age of typhoid immunisation and the choice of vaccines needs to be reassessed. Expand
Salmonella Paratyphi A Rates, Asia
TLDR
Compared their incidences by using standardized methods from population-based studies in China, Indonesia, India, and Pakistan, which found that enteric fever in Asia is caused by Salmonella enterica serovar Typhi and not by S. Paratyphi A. Expand
Cross-protection by B subunit-whole cell cholera vaccine against diarrhea associated with heat-labile toxin-producing enterotoxigenic Escherichia coli: results of a large-scale field trial.
TLDR
Sixty-seven percent fewer episodes of LT-ETEC diarrhea were noted in the BS-WC group than in the WC group during short-term follow-up, but no reduction was evident during the ensuing nine months. Expand
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