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C-4 methylsterol oxidase activity
Known as:
4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,NAD(P)H:oxygen oxidoreductase (hydroxylating)
, 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol,hydrogen-donor:oxygen oxidoreductase (hydroxylating)
, 4-methylsterol oxidase activity
Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)H + H(+) + O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha…
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National Institutes of Health
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2009
2009
Demonstration of a peroxide shunt in the tetrahydropterin-dependent aromatic amino acid monooxygenases.
J. A. Pavon
,
P. Fitzpatrick
Journal of the American Chemical Society
2009
Corpus ID: 207137575
The nonheme iron enzyme phenylalanine hydroxylase, tyrosine hydroxylase, and tryptophan hydroxylase catalyze the hydroxylation of…
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2001
2001
Deuterated delta 7-cholestenol analogues as mechanistic probes for wild-type and mutated delta 7-sterol-C5(6)-desaturase.
A. Rahier
Biochemistry
2001
Corpus ID: 26239709
Deuterium-labeled 5alpha-cholest-7-en-3beta-ol (1) bearing one or two deuteriums at the C-5alpha and (or) C-6alpha positions was…
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1978
1978
Sterol synthesis. Chemical synthesis, structure determination and metabolism of 14 alpha-methyl-5 alpha-cholest-7-en-3 beta, 15 beta-diol and 14 alpha-methyl-5 alpha-cholest-7-en-3 beta, 15 alpha…
T. Spike
,
J. A. Martin
,
S. Huntoon
,
A. Wang
,
F. F. Knapp
,
G. Schroepfer
Chemistry and Physics of Lipids
1978
Corpus ID: 10476554
14alpha-Methyl-5alpha-cholest-7-en-3beta,15beta-diol and 14alpha-methyl-5alpha-cholest-7-en-3beta,15alpha-diol have been prepared…
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Highly Cited
1977
Highly Cited
1977
Inhibition of sterol biosynthesis in L cells and mouse liver cells by 15-oxygenated sterols.
G. Schroepfer
,
E. Parish
,
H. W. Chen
,
A. Kandutsch
Journal of Biological Chemistry
1977
Corpus ID: 30654075
1977
1977
Sterol synthesis. Syntheses of 15-oxygenated 5alpha, 14beta-cholest-7-en-3beta-ol derivatives.
E. Parish
,
G. Schroepfer
Chemistry and Physics of Lipids
1977
Corpus ID: 25060983
Treatment of 3beta-benzoyloxy-14alpha, 15alpha-epoxy-5alpha-cholest-7-ene with boron trifluoride-etherate gave, in 43% yield…
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1976
1976
Purification of a soluble rat liver protein that stimulates microsomal 4-methyl sterol oxidase activity.
J. Gaylor
,
C. V. Delwiche
Journal of Biological Chemistry
1976
Corpus ID: 12004562
1975
1975
The conversion of cholest-5-en-3beta-ol into cholest-7-en-3beta-ol by the echinoderms Asterias rubens and Solaster papposus.
A. Smith
,
L. Goad
Biochemical Journal
1975
Corpus ID: 154302
1. The echinoderms Asterias rubens and Solaster papposus (Class Asteroidea) metabolize injected [4(-14)C]cholest-5-en-3beta-ol to…
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1975
1975
Neutral lipids from the skin of the rhino mutant mouse.
M. Logani
,
W. A. Austin
,
D. B. Nhari
,
R. Davies
Biochimica et Biophysica Acta
1975
Corpus ID: 22505087
1973
1973
The sterols of the echinoderm Asterias rubens.
A. Smith
,
I. Rubinstein
,
L. Goad
Biochemical Journal
1973
Corpus ID: 30593590
1. Twenty-two sterols were identified in the starfish Asterias rubens (Phylum, Echinodermata; Class, Asteroidea). 2. The major 4…
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1972
1972
A novel olefinic rearrangement. The enzymic conversion of cholesta-7,9-dien-3 -ol into cholesta-8,14-dien-3 -ol.
M. Akhtar
,
C. W. Freeman
,
A. Rahimtula
,
D. Wilton
Biochemical Journal
1972
Corpus ID: 37387722
1. [3alpha-(3)H]Cholesta-7,9-dien-3beta-ol is converted in high yield into cholesterol by a 10000g(av.) supernatant fraction of…
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