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Bupropion
Known as:
Amfebutamone
, (+-)-1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
, BUP
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An aminoketone with antidepressant activity. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not…
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National Institutes of Health
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Related topics
Related topics
39 relations
12 HR Bupropion Hydrochloride 100 MG Extended Release Oral Tablet [Wellbutrin]
12 HR Bupropion Hydrochloride 150 MG Extended Release Oral Tablet
24 HR Bupropion Hydrochloride 300 MG Extended Release Oral Tablet [Wellbutrin]
24 HR Bupropion hydrobromide 348 MG Extended Release Oral Tablet [Aplenzin]
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Broader (5)
Antidepressive Agents
Antidepressive Agents, Second-Generation
Bupropion Hydrochloride
Cytochrome P-450 CYP2D6 Inhibitors
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Narrower (9)
Aplenzin
Budeprion
Contrave
Quomen
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis
A. Cipriani
,
T. Furukawa
,
+9 authors
C. Barbui
The Lancet
2009
Corpus ID: 35858125
Highly Cited
2006
Highly Cited
2006
Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression.
A. Rush
,
M. Trivedi
,
+10 authors
M. Fava
The New England journal of medicine
2006
Corpus ID: 19590774
BACKGROUND After unsuccessful treatment for depression with a selective serotonin-reuptake inhibitor (SSRI), it is not known…
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Highly Cited
2006
Highly Cited
2006
Efficacy of Varenicline, an 42 Nicotinic Acetylcholine Receptor Partial Agonist, vs Placebo or Sustained-Release Bupropion for Smoking Cessation A Randomized Controlled Trial
D. Jorenby
,
J. T. Hays
,
+6 authors
K. Reeves
2006
Corpus ID: 74668589
ContextVarenicline, a partial agonist at the α4β2 nicotinic acetylcholine receptor, has the potential to aid smoking cessation by…
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Highly Cited
2006
Highly Cited
2006
Varenicline, an α4β2 Nicotinic Acetylcholine Receptor Partial Agonist, vs Sustained-Release Bupropion and Placebo for Smoking Cessation: A Randomized Controlled Trial
D. Gonzales
,
S. Rennard
,
+7 authors
K. Reeves
2006
Corpus ID: 21739927
ContextThe α4β2 nicotinic acetylcholine receptors (nAChRs) are linked to the reinforcing effects of nicotine and maintaining…
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Highly Cited
2004
Highly Cited
2004
Sequenced treatment alternatives to relieve depression (STAR*D): rationale and design.
A. Rush
,
M. Fava
,
+17 authors
G. Niederehe
Controlled clinical trials
2004
Corpus ID: 29026502
Highly Cited
2003
Highly Cited
2003
Nicotine replacement therapy in smoking cessation.
I. Campbell
Thorax
2003
Corpus ID: 29232863
Evidence for benefit from nicotine replacement therapy in hospital patients is inconclusive, although the results of a trial…
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Highly Cited
2000
Highly Cited
2000
Bupropion is a nicotinic antagonist.
J. Slemmer
,
B. Martin
,
M. Damaj
The Journal of pharmacology and experimental…
2000
Corpus ID: 46592745
Neuronal nicotinic receptors are ligand-gated ion channels of the central and peripheral central nervous system that regulate…
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Highly Cited
1999
Highly Cited
1999
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
D. Jorenby
,
S. Leischow
,
+9 authors
T. Baker
The New England journal of medicine
1999
Corpus ID: 45565436
BACKGROUND AND METHODS Use of nicotine-replacement therapies and the antidepressant bupropion helps people stop smoking. We…
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Highly Cited
1997
Highly Cited
1997
A Comparison of Sustained-Release Bupropion and Placebo for Smoking Cessation
R. Hurt
,
D. Sachs
,
+9 authors
P. Sullivan
1997
Corpus ID: 51754385
Background and Methods Trials of antidepressant medications for smoking cessation have had mixed results. We conducted a double…
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Review
1995
Review
1995
Bupropion: a review of its mechanism of antidepressant activity.
J. Ascher
,
J. Cole
,
+7 authors
E. Richelson
The Journal of clinical psychiatry
1995
Corpus ID: 7702990
BACKGROUND The mechanism of action of the novel antidepressant bupropion remains unclear after many years of study. A review of…
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