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Bupropion

Known as: Amfebutamone, (+-)-1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone, BUP 
An aminoketone with antidepressant activity. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Purpose of ReviewObesity is a global health crisis with detrimental effects on all organ systems leading to worsening disease… Expand
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Review
2017
Review
2017
Summary Objective To review the efficacy, safety, and clinical applicability of liraglutide for weight management from phase III… Expand
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Highly Cited
2010
Highly Cited
2010
BACKGROUND Despite increasing public health concerns regarding obesity, few safe and effective drug treatments are available… Expand
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Highly Cited
2006
Highly Cited
2006
BACKGROUND After unsuccessful treatment for depression with a selective serotonin-reuptake inhibitor (SSRI), it is not known… Expand
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Highly Cited
2006
Highly Cited
2006
CONTEXT Varenicline, a partial agonist at the alpha4beta2 nicotinic acetylcholine receptor, has the potential to aid smoking… Expand
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Highly Cited
2006
Highly Cited
2006
CONTEXT The alpha4beta2 nicotinic acetylcholine receptors (nAChRs) are linked to the reinforcing effects of nicotine and… Expand
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Highly Cited
2006
Highly Cited
2006
ContextThe α4β2 nicotinic acetylcholine receptors (nAChRs) are linked to the reinforcing effects of nicotine and maintaining… Expand
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Highly Cited
2000
Highly Cited
2000
Neuronal nicotinic receptors are ligand-gated ion channels of the central and peripheral central nervous system that regulate… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND AND METHODS Use of nicotine-replacement therapies and the antidepressant bupropion helps people stop smoking. We… Expand
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Highly Cited
1997
Highly Cited
1997
BACKGROUND AND METHODS Trials of antidepressant medications for smoking cessation have had mixed results. We conducted a double… Expand
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