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Bupropion

Known as: Amfebutamone, (+-)-1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone, BUP 
An aminoketone with antidepressant activity. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not… 
National Institutes of Health

Related topics

Related topics

39 relations
12 HR Bupropion Hydrochloride 100 MG Extended Release Oral Tablet [Wellbutrin]12 HR Bupropion Hydrochloride 150 MG Extended Release Oral Tablet24 HR Bupropion Hydrochloride 300 MG Extended Release Oral Tablet [Wellbutrin]24 HR Bupropion hydrobromide 348 MG Extended Release Oral Tablet [Aplenzin]

Broader (5)

Antidepressive AgentsAntidepressive Agents, Second-GenerationBupropion HydrochlorideCytochrome P-450 CYP2D6 Inhibitors

Narrower (9)

AplenzinBudeprionContraveQuomen

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The effect of buprenorphine and bupropion in the treatment of methamphetamine dependency and craving.
Background: Methamphetamine dependency and abuse is a growing problem in the world. Objective: To compare efficacy of… 
Highly Cited
2007
Highly Cited
2007
Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study.
OBJECTIVE Zonisamide and bupropion have been investigated for weight reduction in obese adults. We conducted a preliminary study… 
2000
2000
[Successful treatment of depression in a Parkinson disease patient with bupropion].
A 70-year-old female patient with Parkinson's disease was admitted to hospital with a medication-resistant depression… 
1985
1985
Stability of bupropion and its major metabolites in human plasma.
Bupropion (BUP) is a new, monocyclic, second-generation antidepressant with efficacy comparable with that of the tricyclics but… 
Highly Cited
1984
Highly Cited
1984
Butylphenyl dGTP: a selective and potent inhibitor of mammalian DNA polymerase alpha.
BuPdGTP , the 2'-deoxyribonucleoside 5'-triphosphate of the DNA polymerase alpha (pol alpha)-specific inhibitor, N2-(p-n… 
1983
1983
Effects of bupropion on body weight.
Patients' weights were assessed during placebo-controlled, amitriptyline-controlled, and uncontrolled bupropion trials. Low… 
Review
1983
Review
1983
Clinical pharmacokinetics of bupropion: a review.
: Bupropion is absorbed rapidly after single-dose oral administration of tablets, capsules, or aqueous solution of the… 
1983
1983
Use of bupropion in patients who exhibit orthostatic hypotension on tricyclic antidepressants.
Patients who developed clinically significant and documented orthostatic hypotension during treatment with tricyclic… 
1983
1983
The chemistry of bupropion.
The chemical structure and synthesis of bupropion are described and compared with typical polycyclic antidepressants to point up… 
1983
1983
Psychopharmacology of bupropion in normal volunteers.
In each of four studies of the human pharmacology of bupropion, 12 healthy volunteers received 6 different treatments, including… 
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