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Bupropion

Known as: Amfebutamone, (+-)-1-(3-Chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone, BUP 
An aminoketone with antidepressant activity. The molecular mechanism of the antidepressant effect of bupropion is unknown. This agent does not… Expand
National Institutes of Health

Related topics

Related topics

39 relations
12 HR Bupropion Hydrochloride 100 MG Extended Release Oral Tablet [Wellbutrin]12 HR Bupropion Hydrochloride 150 MG Extended Release Oral Tablet24 HR Bupropion Hydrochloride 300 MG Extended Release Oral Tablet [Wellbutrin]24 HR Bupropion hydrobromide 348 MG Extended Release Oral Tablet [Aplenzin]
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Broader (5)

Antidepressive AgentsAntidepressive Agents, Second-GenerationBupropion HydrochlorideCytochrome P-450 CYP2D6 Inhibitors
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Narrower (9)

AplenzinBudeprionContraveQuomen
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Future Pharmacotherapy for Obesity: New Anti-obesity Drugs on the Horizon
Purpose of ReviewObesity is a global health crisis with detrimental effects on all organ systems leading to worsening disease… Expand
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Review
2017
Review
2017
Liraglutide for weight management: a critical review of the evidence
Summary Objective To review the efficacy, safety, and clinical applicability of liraglutide for weight management from phase III… Expand
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Highly Cited
2010
Highly Cited
2010
Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial
BACKGROUND Despite increasing public health concerns regarding obesity, few safe and effective drug treatments are available… Expand
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Highly Cited
2006
Highly Cited
2006
Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression.
BACKGROUND After unsuccessful treatment for depression with a selective serotonin-reuptake inhibitor (SSRI), it is not known… Expand
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Highly Cited
2006
Highly Cited
2006
Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial.
CONTEXT Varenicline, a partial agonist at the alpha4beta2 nicotinic acetylcholine receptor, has the potential to aid smoking… Expand
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Highly Cited
2006
Highly Cited
2006
Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial.
CONTEXT The alpha4beta2 nicotinic acetylcholine receptors (nAChRs) are linked to the reinforcing effects of nicotine and… Expand
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Highly Cited
2006
Highly Cited
2006
Varenicline, an α4β2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: A randomized controlled trial
ContextThe α4β2 nicotinic acetylcholine receptors (nAChRs) are linked to the reinforcing effects of nicotine and maintaining… Expand
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Highly Cited
2000
Highly Cited
2000
Bupropion is a nicotinic antagonist.
Neuronal nicotinic receptors are ligand-gated ion channels of the central and peripheral central nervous system that regulate… Expand
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Highly Cited
1999
Highly Cited
1999
A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation.
BACKGROUND AND METHODS Use of nicotine-replacement therapies and the antidepressant bupropion helps people stop smoking. We… Expand
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Highly Cited
1997
Highly Cited
1997
A comparison of sustained-release bupropion and placebo for smoking cessation.
BACKGROUND AND METHODS Trials of antidepressant medications for smoking cessation have had mixed results. We conducted a double… Expand
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