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Bupranolol

Known as: 2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-((1,1-dimethylethyl)amino)-, hydrochloride, (+-)-, Bupranol, Bupranolol [Chemical/Ingredient] 
An adrenergic-beta-2 antagonist that has been used for cardiac arrhythmia, angina pectoris, hypertension, glaucoma, and as an antithrombotic.
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
A reservoir-type transdermal delivery system (TDS) of bupranolol (BPL) was designed and evaluated for different formulation… Expand
Highly Cited
2005
Highly Cited
2005
Background—The therapeutic effects of nonspecific β-blockers are limited by vasoconstriction, thus justifying the interest in… Expand
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Highly Cited
2004
Highly Cited
2004
Transdermal absorption of drugs is limited by the stratum corneum, which serves as a diffusion barrier. This barrier might be… Expand
Highly Cited
2004
Highly Cited
2004
Bupranolol (BPL) is a potent beta-blocking agent, the extensive first-pass metabolism (>90%) and rapid elimination half-life (1.5… Expand
Highly Cited
2001
Highly Cited
2001
Abstract— Altered expression and functional responses to cardiac &bgr;3-adrenergic receptors (ARs) may contribute to progressive… Expand
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Highly Cited
1999
Highly Cited
1999
PURPOSE To investigate the presence of the beta3-adrenoceptor (beta3-AR) in human and rat detrusor muscle and the usefulness of… Expand
Highly Cited
1999
Highly Cited
1999
Abstract Numerous synthetic agonists selectively stimulate β3-adrenoceptors (ARs). The endogenous catecholamines, noradrenaline… Expand
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Highly Cited
1998
Highly Cited
1998
The role of beta3- and other putative atypical beta-adrenoceptors in human white adipocytes and right atrial appendage has been… Expand
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Highly Cited
1996
Highly Cited
1996
Beta3-adrenoceptors are involved in metabolism, gut relaxation, and vascular vasodilation. However, their existence and role in… Expand
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Highly Cited
1993
Highly Cited
1993
With respect to the beta 1- and beta 2-adrenergic receptors (ARs), the beta 3-AR induces specific physiological effects in a few… Expand