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Bromouracil

Known as: 5 BrU, Bromouracil [Chemical/Ingredient], 5-Bromouracil 
5-Bromo-2,4(1H,3H)-pyrimidinedione. Brominated derivative of uracil that acts as an antimetabolite, substituting for thymine in DNA. It is used… 
National Institutes of Health

Related topics

Related topics

18 relations

Narrower (7)

1-amino-5-bromouracil1-methyl-5-bromouracil5-(2-bromovinyl)uracil5-bromo-1,3,6-trimethyluracil

Broader (4)

AntimetabolitesMutagenshalouraciluracil analog
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Highly Cited
1986
Highly Cited
1986
The effects of base analogue substitutions on the cleavage by the EcoRI restriction endonuclease of octadeoxyribonucleotides containing modified EcoRI recognition sequences.
Highly Cited
1968
Highly Cited
1968
Rates of chain growth and units of replication in DNA of mammalian chromosomes.
Highly Cited
1967
Highly Cited
1967
Properties of the growing point region in the bacterial chromosome.
Highly Cited
1967
Highly Cited
1967
Sequential replication of the Bacillus subtilis chromosome. IV. Genetic mapping by density transfer experiment.
Highly Cited
1966
Highly Cited
1966
Molecular mechanisms of genetic recombination in bacteriophage. VI. A mutant defective in the joining of DNA molecules.
Highly Cited
1963
Highly Cited
1963
THE EFFECT OF AMINO ACID DEPRIVATION ON SUBSEQUENT DEOXYRIBONUCLEIC ACID REPLICATION.
Highly Cited
1962
Highly Cited
1962
Helix-random coil transitions in synthetic DNAs of alternating sequence.
Highly Cited
1961
Highly Cited
1961
The normal DNA replication cycle. II.
Highly Cited
1960
Highly Cited
1960
Studies on ultraviolet irradiation of Escherichia coli containing 5-bromouracil in its DNA.
SUMMARY: Thymine-requiring Escherichia coli 15, t– and E. coli B, t– which contained 5-bromouracil in their deoxyribonucleic acid… 
Highly Cited
1957
Highly Cited
1957
Effects of 5-halogenated uracils on the growth of Escherichia coli and their incorporation into deoxyribonucleic acids.
A variety of structural analogues of purines and pyrimidines are known to affect the growth of viruses, bacteria and other micro… 
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