Brefeldin A

Known as: Ascotoxin, 4H-Cyclopent(f)oxacyclotridecin-4-one,1,6,7,8,9,11a-beta,12,13,14,14a-alpha-decahydro-1-beta-13-alpha-dihydroxy-6-beta-methyl-, Synergisidin 
A fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1957-2018
0204019572017

Papers overview

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Highly Cited
2005
Highly Cited
2005
Trafficking through the Golgi apparatus requires members of the Arf family of GTPases, whose activation is regulated by guanine… (More)
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Highly Cited
2003
Highly Cited
2003
Exchange factors for ARF GTPases (ARF-GEFs) regulate vesicle trafficking in a variety of organisms. The Arabidopsis protein GNOM… (More)
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Highly Cited
2002
Highly Cited
2002
Brefeldin A (BFA) causes a block in the secretory system of eukaryotic cells by inhibiting vesicle formation at the Golgi… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The terminal phase of cytokinesis in eukaryotic cells involves breakage of the intercellular canal containing the… (More)
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Highly Cited
1992
Highly Cited
1992
Brefeldin A (BFA) causes a rapid redistribution of coat proteins (e.g., gamma-adaptin) associated with the clathrin-coated… (More)
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Highly Cited
1991
Highly Cited
1991
Addition of brefeldin A (BFA) to most cells results in both the formation of extensive, uncoated membrane tubules through which… (More)
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Highly Cited
1991
Highly Cited
1991
Brefeldin A (BFA) is a fungal metabolite that causes a redistribution of the stacked cisternae of the Golgi complex into the… (More)
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Highly Cited
1990
Highly Cited
1990
Characteristics of brefeldin A (BFA)-induced redistribution of Golgi proteins into the endoplasmic reticulum (ER) and its… (More)
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Highly Cited
1989
Highly Cited
1989
In cells treated with brefeldin A (BFA), movement of newly synthesized membrane proteins from the endoplasmic reticulum (ER) to… (More)
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Highly Cited
1989
Highly Cited
1989
Brefeldin A (BFA) has been reported to block protein transport from the ER and cause disassembly of the Golgi complex. We have… (More)
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