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Propafenone

Known as: Propafenona, Propafenone [Chemical/Ingredient], 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone 
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
National Institutes of Health

Related topics

Related topics

41 relations
12 HR Propafenone Hydrochloride 225 MG Extended Release Oral CapsuleAmprenavirAtrial FibrillationBradycardia

Narrower (10)

5-hydroxypropafenoneBaxarytmonFenoprainN-depropylpropafenone

Broader (2)

Anti-Arrhythmia AgentsVoltage-Gated Sodium Channel Blockers

Papers overview

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1987
1987
Lack of clinically significant beta-blocking effect of propafenone.
To study possible beta-blocking effects of propafenone, a class 1c antiarrhythmic agent, electrocardiographic variables were… 
1986
1986
Influence of Protein Binding on the Myocardial Uptake and Pharmacodynamics of Propafenone
The relationship between plasma protein binding, myocardial uptake, and cardiac pharmacodynamics of propafenone was studied in an… 
1985
1985
Malignant ventricular tachyarrhythmias in association with propafenone treatment.
During treatment with the class Ic antiarrhythmic agent propafenone, the drug appeared to cause malignant ventricular… 
1985
1985
Pharmacokinetics of intravenous propafenone in patients with episodes of paroxysmal supraventricular tachycardia.
The plasma concentration time curves of propafenone after administration of single i.v. (2.3 +/- 0.2 mg/kg) doses have been… 
1984
1984
Fatal ventricular tachycardia in association with propafenone, a new class IC antiarrhythmic agent.
A man with a past history of malignant ventricular arrhythmias occurring late after myocardial infarction was admitted for… 
Highly Cited
1982
Highly Cited
1982
Suppression of Ventricular Arrhythmias by Propafenone, a New Antiarrhythmic Agent, During Acute Myocardial Infarction in the Conscious Dog A Comparative Study with Lidocaine
The responsiveness of ventricular tachycardia (VT) to propafenone, a new antiarrhythmic agent, was evaluated in the conscious dog… 
1982
1982
[Studies on the analysis of propafenone by means of internal analogue standardization (author's transl)].
A high-pressure liquid chromatographic method with internal analogue standardization is described for the determination of 2'-(2… 
Highly Cited
1981
Highly Cited
1981
Electrophysiological effects of propafenone studied with programmed electrical stimulation of the heart in patients with recurrent paroxysmal supraventricular tachycardia.
Propafenone is an antiarrhythmic which possesses the properties of a class I agent. Its electrophysiological effects were studied… 
1980
1980
Serial electrophysiological testing of antiarrhythmic drug efficacy in patients with recurrent ventricular tachycardia.
The purpose of the present study was to determine the predictive value of serial electrophysiological testing during… 
1978
1978
[Indications and risks of anti-arrhythmia treatment with propafenone (author's transl)].
Propafenone, a new anti-arrhythmia drug, was given at an average dose of 70-140 mg (1-2 mg/kg body-weight) to 124 patients with…