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Propafenone

Known as: Propafenona, Propafenone [Chemical/Ingredient], 1-(2-(2-Hydroxy-3-(propylamino)propoxy)phenyl)-3-phenyl-1-propanone 
An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
National Institutes of Health

Related topics

Related topics

41 relations
12 HR Propafenone Hydrochloride 225 MG Extended Release Oral CapsuleAmprenavirAtrial FibrillationBradycardia

Narrower (10)

5-hydroxypropafenoneBaxarytmonFenoprainN-depropylpropafenone

Broader (2)

Anti-Arrhythmia AgentsVoltage-Gated Sodium Channel Blockers

Papers overview

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2005
2005
Interaction field based and hologram based QSAR analysis of propafenone-type modulators of multidrug resistance.
Overexpression of membrane bound, ATP-dependent transport proteins is one of the predominant mechanisms leading to multiple drug… 
2005
2005
Estudio farmacogenético de la respuesta a flecainida y propafenona en pacientes con fibrilación auricular
Se analizo el polimorfismo del citocromo P450-2D6 mediante la determinacion del fenotipo, utilizando la ratio entre… 
2002
2002
Desenmascaramiento del "síndrome de Brugada" con propafenona endovenosa
Presentamos el caso de una mujer de 39 anos de edad con antecedentes familiares de un hermano que fallecio subitamente a la edad… 
1989
1989
In-vitro plasma protein binding of propafenone and protein profile in eight mammalian species.
The protein binding of propafenone in vitro was assessed in plasma of mouse, rat, rabbit, dog, sheep, man, cow, and horse at two… 
1987
1987
Torsade de pointes ventricular tachycardia in a hypothyroid patient treated with propafenone.
A 31-year-old female had recurring palpitations and black-outs for 13 years. Hyperthyroidism was diagnosed and electrocardiogram… 
1982
1982
[Studies on the analysis of propafenone by means of internal analogue standardization (author's transl)].
A high-pressure liquid chromatographic method with internal analogue standardization is described for the determination of 2'-(2… 
1980
1980
Serial electrophysiological testing of antiarrhythmic drug efficacy in patients with recurrent ventricular tachycardia.
The purpose of the present study was to determine the predictive value of serial electrophysiological testing during… 
1978
1978
[Indications and risks of anti-arrhythmia treatment with propafenone (author's transl)].
Propafenone, a new anti-arrhythmia drug, was given at an average dose of 70-140 mg (1-2 mg/kg body-weight) to 124 patients with… 
1977
1977
[Long-term treatment with the new antiarrhythmic drug propafenone in correlation to plasma levels (author's transl)].
The results of long term oral therapy of cardiac arrhythmias in 43 patients successfully treated with propafenone are reported… 
1976
1976
[Pharmacology of 2'-[2-hydroxy-3-(propylamino)-propoxy]-3-phenylpropiophenone (Propafenone, SA 79)-hydrochloride].
The pharmacologic actions of 2'-[2-hydroxy-3-(propylamino)-propoxy]-3-phenylpropiophenone (propafenone, SA 79) hydrochloride were…