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Berberine

Known as: Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, Berberine [Chemical/Ingredient], Umbellatine 
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been… 
National Institutes of Health

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Papers overview

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Highly Cited
2009
Highly Cited
2009
Berberine suppresses proinflammatory responses through AMPK activation in macrophages.
Berberine (BBR) has been shown to improve several metabolic disorders, such as obesity, type 2 diabetes, and dyslipidemia, by… 
Highly Cited
2009
Highly Cited
2009
Investigation of the interaction between Berberine and human serum albumin.
Berberine is an important traditional medicinal herb, which has been effectively used in the treatment of dysentery, diarrhea… 
Review
2008
Review
2008
Pharmacological and therapeutic effects of Berberis vulgaris and its active constituent, berberine
Barberry (Berberis vulgaris L. family Berberidaceae) is well known in Iran and various parts of this plant including its root… 
Highly Cited
2008
Highly Cited
2008
Berberine improves glucose metabolism through induction of glycolysis.
Berberine, a botanical alkaloid used to control blood glucose in type 2 diabetes in China, has recently been reported to activate… 
Highly Cited
2008
Highly Cited
2008
Efficacy of berberine in patients with type 2 diabetes mellitus.
Highly Cited
2008
Highly Cited
2008
Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
CONTEXT Berberine, a natural plant alkaloid, is usually used as an antibiotic drug. The potential glucose-lowering effect of… 
Highly Cited
2006
Highly Cited
2006
Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States
Berberine has been shown to have antidiabetic properties, although its mode of action is not known. Here, we have investigated… 
Highly Cited
2004
Highly Cited
2004
Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins
We identify berberine (BBR), a compound isolated from a Chinese herb, as a new cholesterol-lowering drug. Oral administration of… 
Highly Cited
2000
Highly Cited
2000
Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor.
Multidrug resistance pumps (MDRs) protect microbial cells from both synthetic and natural antimicrobials. Amphipathic cations are… 
Highly Cited
1969
Highly Cited
1969
Berberine sulfate: antimicrobial activity, bioassay, and mode of action.
Berberine sulfate was shown to possess antimicrobial activity against a wide variety of microorganisms including Gram-positive… 
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