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Berberine

Known as: Benzo(g)-1,3-benzodioxolo(5,6-a)quinolizinium, 5,6-dihydro-9,10-dimethoxy-, Berberine [Chemical/Ingredient], Umbellatine 
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been… 
National Institutes of Health

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Berberine ChlorideIn Bloodagonistsanalogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Berberis Vulgaris and Berberine: An Update Review
Berberine is an isoquinoline alkaloid present in several plants, including Coptis sp. and Berberis sp. Berberine is a customary… 
Highly Cited
2014
Highly Cited
2014
The crosstalk between Nrf2 and AMPK signal pathways is important for the anti-inflammatory effect of berberine in LPS-stimulated macrophages and endotoxin-shocked mice.
AIMS The response of AMP-activated protein kinase (AMPK) to oxidative stress has been recently reported but the downstream… 
Highly Cited
2010
Highly Cited
2010
Extensive Intestinal First-Pass Elimination and Predominant Hepatic Distribution of Berberine Explain Its Low Plasma Levels in Rats
Berberine, one of the most commonly used natural products, exhibits a poor plasma concentration-effect relationship whose… 
Highly Cited
2010
Highly Cited
2010
TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling
TNFα-mediated tight junction defects contribute to diarrhea in inflammatory bowel diseases (IBDs). In our study, the signaling… 
Review
2010
Review
2010
Regulation of survival, proliferation, invasion, angiogenesis, and metastasis of tumor cells through modulation of inflammatory pathways by nutraceuticals
Almost 25 centuries ago, Hippocrates, the father of medicine, proclaimed “Let food be thy medicine and medicine be thy food… 
Highly Cited
2009
Highly Cited
2009
Berberine suppresses proinflammatory responses through AMPK activation in macrophages.
Berberine (BBR) has been shown to improve several metabolic disorders, such as obesity, type 2 diabetes, and dyslipidemia, by… 
Highly Cited
2008
Highly Cited
2008
Berberine targets assembly of Escherichia coli cell division protein FtsZ.
The ever increasing problem of antibiotic resistance necessitates a search for new drug molecules that would target novel… 
Review
2006
Review
2006
Cardiovascular actions of berberine.
Berberine, is an alkaloid from Hydrastis canadensis L., Chinese herb Huanglian, and many other plants. It is widely used in… 
Highly Cited
1997
Highly Cited
1997
Berberine: Therapeutic Potential of an Alkaloid Found in Several Medicinal Plants
Berberine-containing plants are used medicinally in virtually all traditional medical systems, and have a history of usage in… 
Highly Cited
1969
Highly Cited
1969
Berberine sulfate: antimicrobial activity, bioassay, and mode of action.
Berberine sulfate was shown to possess antimicrobial activity against a wide variety of microorganisms including Gram-positive… 
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