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Benzomorphans

Known as: Benzomorphans [Chemical/Ingredient] 
Morphine derivatives of the methanobenzazocine family that act as potent analgesics.
National Institutes of Health

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19 relations

Narrower (13)

BIII 277 CLBIII 890 CLBenzomorphanGPA 1657
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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Review
2015
Review
2015
Sigma receptors [σRs]: biology in normal and diseased states
Abstract This review compares the biological and physiological function of Sigma receptors [σRs] and their potential therapeutic… 
Review
2004
Review
2004
Neurosteroids and σ1 Receptors, Biochemical and Behavioral Relevance
de novo 
Highly Cited
2003
Highly Cited
2003
σ-1 Receptors (σ1 Binding Sites) Form Raft-Like Microdomains and Target Lipid Droplets on the Endoplasmic Reticulum: Roles in Endoplasmic Reticulum Lipid Compartmentalization and Export
The brain σ-1 receptors can bind neurosteroids and psychotropic drugs, including neuroleptics and cocaine and are implicated in… 
1997
1997
Presence and characterization of nociceptin (orphanin FQ) receptor binding in adult rat and human fetal hypothalamus
Highly Cited
1993
Highly Cited
1993
A comparison of (-)-deoxybenzomorphans devoid of opiate activity with their dextrorotatory phenolic counterparts suggests role of sigma 2 receptors in motor function.
Review
1991
Review
1991
Sigma receptors. Putative links between nervous, endocrine and immune systems.
The sigma receptor is a neuronal substrate that binds several psychoactive compounds. These include cocaine, some steroids… 
Review
1990
Review
1990
Sigma binding sites in the brain; an emerging concept for multiple sites and their relevance for psychiatric disorders.
Highly Cited
1984
Highly Cited
1984
κ and δ-opioid receptor agonists differentially inhibit striatal dopamine and acetylcholine release
At least three different families of endogenous opioid peptides, the enkephalins, endorphins and dynorphins, are present in the… 
Highly Cited
1981
Highly Cited
1981
UNEXPECTED ANTAGONISM IN THE RAT VAS DEFERENS BY BENZOMORPHANS WHICH ARE AGONISTS IN OTHER PHARMACOLOGICAL TESTS
The benzomorphans, ethylketazocine, bremazocine and MR 2034 are pure agonists in the guinea‐pig ileum and mouse vas deferens but… 
Highly Cited
1975
Highly Cited
1975
ASSESSMENT IN THE GUINEA‐PIG ILEUM AND MOUSE VAS DEFERENS OF BENZOMORPHANS WHICH HAVE STRONG ANTINOCICEPTIVE ACTIVITY BUT DO NOT SUBSTITUTE FOR MORPHINE IN THE DEPENDENT MONKEY
1 Four benzomorphans which have potent antinociceptive activity in the hot‐plate and writhing tests in the mouse but do not… 
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