BUB1 gene

Known as: BUB1 mitotic checkpoint serine/threonine kinase, BUB1 Mitotic Checkpoint Serine/Threonine Kinase Gene, BUB1, S. CEREVISIAE, HOMOLOG OF 
This gene is a modulator of the mitotic spindle cell cycle checkpoint.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2017
051019942017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Fidelity of chromosome segregation relies on coordination of chromosome biorientation and the spindle checkpoint. Central to this… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Bub1 is a component of the spindle assembly checkpoint (SAC), a surveillance mechanism that ensures genome stability by delaying… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2007
2007
The spindle checkpoint that monitors kinetochore-microtubule attachment has been implicated in tumorigenesis; however, the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2004
2004
Proper kinetochore function is essential for the accurate segregation of chromosomes during mitosis. Kinetochores provide the… (More)
Is this relevant?
2003
2003
The mitotic spindle assembly checkpoint modulates the timing of anaphase initiation in response to improper alignment of… (More)
Is this relevant?
2003
2003
The spindle checkpoint ensures accurate chromosome segregation by delaying anaphase until all chromosomes are correctly aligned… (More)
Is this relevant?
2003
2003
Endometrial carcinoma (EC) comprises at least two types of cancer: endometrioid carcinomas (EECs) are estrogen-related tumors… (More)
  • figure 1
  • table 1
Is this relevant?
2000
2000
It has been established that mutations in Drosophila Polo cause abnormalities in mitosis. In human cells, maximal Plk activity is… (More)
  • table 1
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Genetic instability was one of the first characteristics to be postulated to underlie neoplasia. Such genetic instability occurs… (More)
Is this relevant?
Highly Cited
1994
Highly Cited
1994
Normal cell multiplication requires that the events of mitosis occur in a carefully ordered fashion. Cells employ checkpoints to… (More)
Is this relevant?