BUB1B wt Allele

Known as: Mitotic Checkpoint Gene BUB1B, hBUBR1, SSK1 
Human BUB1B wild-type allele is located in the vicinity of 15q15 and is approximately 60 kb in length. This allele, which encodes mitotic checkpoint… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Maintenance of chromosomal stability depends on error-free chromosome segregation. The pseudokinase BUBR1 is essential for this… (More)
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Highly Cited
2005
Highly Cited
2005
Thiol proteins are important in cellular antioxidant defenses and redox signalling. It is postulated that reactive oxidants cause… (More)
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Highly Cited
2005
Highly Cited
2005
The spindle checkpoint maintains genome stability by inhibiting Cdc20-mediated activation of the anaphase promoting complex… (More)
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Highly Cited
2004
Highly Cited
2004
During mitosis, the recruitment of spindle-checkpoint-associated proteins to the kinetochore occurs in a defined order. The… (More)
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Highly Cited
2004
Highly Cited
2004
Paclitaxel stabilizes microtubules, causing mitotic arrest and activating the spindle assembly checkpoint. We determined whether… (More)
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Review
2004
Review
2004
Colorectal cancer affected ∼135,000 people in the United States in 2001, resulting in 57,000 deaths. At the cellular level… (More)
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Highly Cited
2003
Highly Cited
2003
The Aurora/Ipl1 family of protein kinases plays multiple roles in mitosis and cytokinesis. Here, we describe ZM447439, a novel… (More)
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Highly Cited
2003
Highly Cited
2003
The physiologic function of BUBR1, a key component of the spindle checkpoint, was examined by generating BUBR1-mutant mice. BUBR1… (More)
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Highly Cited
2001
Highly Cited
2001
BUB1 is a budding yeast gene required to ensure that progression through mitosis is coupled to correct spindle assembly. Two… (More)
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Highly Cited
1999
Highly Cited
1999
Human cells express two kinases that are related to the yeast mitotic checkpoint kinase BUB1. hBUB1 and hBUBR1 bind to… (More)
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