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BUB1B wt Allele

Known as: Mitotic Checkpoint Gene BUB1B, hBUBR1, SSK1 
Human BUB1B wild-type allele is located in the vicinity of 15q15 and is approximately 60 kb in length. This allele, which encodes mitotic checkpoint… Expand
National Institutes of Health

Papers overview

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Highly Cited
2005
Highly Cited
2005
Loss or gain of whole chromosomes, the form of chromosomal instability (CIN) most commonly associated with human cancers, is… Expand
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Highly Cited
2004
Highly Cited
2004
During mitosis, the recruitment of spindle-checkpoint-associated proteins to the kinetochore occurs in a defined order. The… Expand
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Highly Cited
2004
Highly Cited
2004
A compromised spindle checkpoint is thought to play a key role in genetic instability that predisposes cells to malignant… Expand
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Review
2004
Review
2004
  • W. Grady
  • Cancer and Metastasis Reviews
  • 2004
  • Corpus ID: 1177511
Colorectal cancer affected ∼135,000 people in the United States in 2001, resulting in 57,000 deaths. At the cellular level… Expand
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Highly Cited
2004
Highly Cited
2004
Paclitaxel stabilizes microtubules, causing mitotic arrest and activating the spindle assembly checkpoint. We determined whether… Expand
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Highly Cited
2003
Highly Cited
2003
The Aurora/Ipl1 family of protein kinases plays multiple roles in mitosis and cytokinesis. Here, we describe ZM447439, a novel… Expand
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Highly Cited
2003
Highly Cited
2003
Centromere-associated protein-E (CENP-E) is an essential mitotic kinesin that is required for efficient, stable microtubule… Expand
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Highly Cited
2002
Highly Cited
2002
  • G. Fang
  • Molecular biology of the cell
  • 2002
  • Corpus ID: 39275608
The spindle assembly checkpoint monitors the attachment of kinetochores to the mitotic spindle and the tension exerted on… Expand
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Highly Cited
1999
Highly Cited
1999
Human cells express two kinases that are related to the yeast mitotic checkpoint kinase BUB1. hBUB1 and hBUBR1 bind to… Expand
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Highly Cited
1997
Highly Cited
1997
The development of new nonnucleoside inhibitors of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT) active… Expand
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