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BTLA gene

Known as: CD272, BTLA, B and T lymphocyte associated 
This gene is involved in the immune response.
National Institutes of Health

Related topics

Related topics

3 relations
B- and T-Lymphocyte AttenuatorImmune System ProcessesImmunoregulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Association between BTLA polymorphisms and susceptibility to esophageal squamous cell carcinoma in the Chinese population
Growing evidence suggested that B‐ and T‐lymphocyte attenuator (BTLA) polymorphisms raised the susceptibility to a wide range of… 
2016
2016
BTLA identifies dysfunctional PD-1-expressing CD4+ T cells in human hepatocellular carcinoma
ABSTRACT Although immunotherapy targeting programmed cell death 1/programmed cell death ligand 1 (PD-1/PD-L1) pathway is being… 
2016
2016
Enhanced Innate Inflammation Induced by Anti-BTLA Antibody in Dual Insult Model of Hemorrhagic Shock/Sepsis
ABSTRACT Sepsis following hemorrhagic shock is a common clinical condition, in which innate immune system suffers from severe… 
Review
2012
Review
2012
Coinhibitory Molecules in Autoimmune Diseases
Coinhibitory molecules such as CTLA-4, PD-1 and BTLA negatively regulate immune responses. Multiple studies indicate that the… 
2011
2011
B and T lymphocyte attenuator down-regulation by HIV-1 depends on type I interferon and contributes to T-cell hyperactivation.
BACKGROUND Nonspecific T-cell hyperactivation is the main driving force for human immunodeficiency virus (HIV)-1 disease… 
2010
2010
Association of BTLA gene polymorphisms with the risk of malignant breast cancer in Chinese women of Heilongjiang Province
B and T lymphocyte attenuator (BTLA) is an immunoinhibitory receptor with the ability to deliver inhibitory signals for… 
2010
2010
Activation‐induced accumulation of B and T lymphocyte attenuator at the immunological synapse in CD4+ T cells
BTLA, a recently cloned coreceptor expressed on lymphocytes, negatively regulates cell activation by recruiting SHP‐1/SHP‐2… 
2008
2008
CD160 and BTLA: LIGHTs out for CD4+ T cells
The T cell costimulatory protein LIGHT and coinhbitory protein BTLA share a common ligand, HVEM. Now CD160 is also shown to bind… 
2007
2007
B and T lymphocyte attenuator interacts with CD3ζ and inhibits tyrosine phosphorylation of TCRζ complex during T‐cell activation
B and T lymphocyte attenuator (BTLA) is an important negative regulator of T‐cell activation. T‐cell activation involves… 
Review
2006
Review
2006
Coinhibitory T-Cell Signaling in Islet Allograft Rejection and Tolerance
Autoaggressive T cells directed against insulin secreting pancreatic β-cells mediate the development of type 1 diabetes. Islet… 
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