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BTG2 gene

Known as: PC3, MGC126063, MGC126064 
This gene is involved in the regulation of the G1/S transition of the cell cycle.
National Institutes of Health

Related topics

Related topics

7 relations
BTG1 geneBTG2 protein, humanCell Cycle ControlChronic Lymphocytic Leukemia

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BTG2 wt Allele

Papers overview

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2014
2014
Accumulation of cytolytic CD8+ T cells in B16-melanoma and proliferation of mature T cells in TIS21-knockout mice after T cell receptor stimulation.
2012
2012
TIS21/BTG2/PC3 enhances downregulation of c-Myc during differentiation of HL-60 cells by activating Erk1/2 and inhibiting Akt in response to all-trans-retinoic acid.
Highly Cited
2010
Highly Cited
2010
Impact of BTG2 expression on proliferation and invasion of gastric cancer cells in vitro
BTG2 (B cell translocation gene 2) is downregulated in several human tumors and has been known as a tumor suppressor in… 
Highly Cited
2008
Highly Cited
2008
TIS21 negatively regulates hepatocarcinogenesis by disruption of cyclin B1–Forkhead box M1 regulation loop
A functional and biochemical interaction of TIS21/BTG2/PC3 with Forkhead box M1 (FoxM1), essential transcription factor for… 
2008
2008
TIS21/BTG2 Negatively Regulates Estradiol‐Stimulated Expansion of Hematopoietic Stem Cells by Derepressing Akt Phosphorylation and Inhibiting mTOR Signal Transduction
It has been known that 12‐O‐tetradecanoyl phorbol‐13‐acetate‐inducible sequence 21 (TIS21), ortholog of human B‐cell… 
2005
2005
The BTG/TOB family protein TIS21 regulates stage‐specific proliferation of developing thymocytes
As thymocytes undergo differentiation in the thymus, they progress through distinct phases of quiescence and proliferation… 
2005
2005
Experimental Oncology Differential expression of TIS21 and TIS1 genes in the various organs of Balb/c mice, thymic carcinoma tissues and human cancer cell lines
As a part of a series of investigations on the functions of TIS21 and TIS1 genes, we measuredin vivo 12-O-tetradecanoylphorbol-13… 
2003
2003
PICK1, an Anchoring Protein That Specifically Targets Protein Kinase Cα to Mitochondria Selectively upon Serum Stimulation in NIH 3T3 Cells*
PICK1 binds to protein kinase Cα (PKCα) through the carboxylate-binding loop in its PDZ (PSD95/Disc-large/ZO-1) domain and the C… 
2003
2003
Genes Modulated by Expression of GD3 Synthase in Chinese Hamster Ovary Cells
9-O-Acetylation is a common sialic acid modification, expressed in a developmentally regulated and tissue/cell type-specific… 
1994
1994
Preferential primary‐response gene expression in promotion‐resistant versus promotion‐sensitive JB6 cells
The 12‐O‐tetradecanoylphorbol‐13‐acetate (TPA)‐inducible sequence (TIS) genes are a set of primary response genes induced in… 
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